Results 271 to 280 of about 12,374,157 (394)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Mechanisms of Cell Fusion in Cancer. [PDF]

Results Probl Cell Differ
Noubissi FK, Odubanjo OV, Ogle BM, Tchounwou PB.   +3 more
europepmc   +1 more source

Integrin α₅β₁ contributes to cell fusion and inflammation mediated by SARS-CoV-2 spike via RGD-independent interaction. [PDF]

Proc Natl Acad Sci U S A, 2023
Zhang H, Wang Z, Nguyen HTT, Watson AJ, Lao Q, Li A, Zhu J.   +6 more
europepmc   +1 more source

Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion. [PDF]

, 1987
Thomas J. Matthews, K J Weinhold, H. Kim Lyerly, A J Langlois, Hans Wigzell, Dani P. Bolognesi   +5 more
openalex   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

PKM2 regulates osteoclastogenesis by affecting osteoclast precursor cell fusion via downregulation of OC-STAMP and DC-STAMP. [PDF]

J Biol Chem
Cai C, Jiang J, Li S, Gao C, Pu H, Zhao L, Xiao J.   +6 more
europepmc   +1 more source

Optimization study of plasmonic cell fusion. [PDF]

Sci Rep, 2022
Belansky J, Yelin D.
europepmc   +1 more source

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. [PDF]

, 1989
Nita H. Salzman, Frederick R. Maxfield
openalex   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering. [PDF]

J Virol
Hirai Y, Takemoto R, Yanagi Y, Shirogane Y.   +3 more
europepmc   +1 more source