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Biomechanics of virus-to-cell and cell-to-cell fusion
Journal of Biomedical Engineering, 1984A biomechanical model of virus-to-cell and cell-to-cell fusion is presented. Virus and the cells are modelled as initially spherical membranes of nonlinear elastic material that undergo large deformations. The membranes are connected by a cytoplasmic bridge which expands, resulting in the formation of a larger single sphere.
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Eukaryotic Cell–Cell Fusion Families
2011Abstract The capacity of cells to unite in a regulated fashion, through fusion of their plasma membranes, is essential for reproduction and development in eukaryotes. Yet, the majority of proteins that mediate this process (i.e. fusogens) remain unidentified or uncharacterized.
Ori Avinoam, Benjamin Podbilewicz
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2010
Differentiation, self-renewal and the ability to readily undergo cell fusion are properties of adult and embryonic stem cells. Spontaneous fusion between stem cells, and fusion of stem cells with various differentiated cell types, has been observed in many in vitro and in vivo contexts.
Melissa H. Wong +3 more
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Differentiation, self-renewal and the ability to readily undergo cell fusion are properties of adult and embryonic stem cells. Spontaneous fusion between stem cells, and fusion of stem cells with various differentiated cell types, has been observed in many in vitro and in vivo contexts.
Melissa H. Wong +3 more
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Cell cycle of multinucleate cells after cell fusion
Experimental Cell Research, 1971Summary The cell cycle of binucleate and multinucleate cells was studied after fusion of synchronized cells. A prolongation of the S phase in the nuclei of the binucleate cells was observed. Mitosis was not always synchronized in the homokaryons. The duration of the G1 phase in binucleate S/G1 cells is shortened.
A. Westerveld, Maria A. Freeke
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Fusion of Myeloma Cells with Immune Spleen Cells
Current Protocols in Molecular Biology, 1988AbstractLiquid nitrogen storage is the method of choice for long‐term safekeeping of hybridoma cell lines. Frozen aliquots of originally isolated hybridomas provide insurance against loss of antibody production and vigor during culture. There are many variations of cell freezing methods in use.
Miyoko Takahashi +2 more
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Cell-Cell Fusion, Chemotaxis and Metastasis [PDF]
, 2015 This review covers the concept of cell-cell fusion as an important feature of cancer progression and its consequences. The fusion of abnormal (mutated proliferating) cells with “task force” cells of the immune system (e.g., leukocytes and stem cells) that respond to tissue damage and stress has now been demonstrated.
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Cell Fusion Hypothesis of the Cancer Stem Cell
2011A major advance in recent cancer research is the identification of tumor cells with stem cell-like properties. Cancer stem cells (CSCs) often represent a rare population in the tumor mass and possess the exclusive ability to initiate the growth of a heterogeneous tumor. The origin of CSCs remains elusive and is likely to be cancer type specific.
Xin Lu, Yibin Kang
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Horizontal transmission of malignancy by cell–cell fusion
Expert Opinion on Biological Therapy, 2012The crosstalk between tumor and stromal cells has become an increasing important subject of the biology of oncogenesis, also involving new therapy paradigms for treating tumor-reactive host cells and vasculature.This article describes the long-term propagation in hamsters of a human glioblastoma which was derived from the in-vivo fusion of the human ...
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