Results 381 to 390 of about 12,274,986 (416)

ADAMs and cell fusion

Current Opinion in Cell Biology, 1996
Members of the ADAM family (membrane proteins with a disintegrin and metalloprotease domain) have been implicated in several cell-interactive events, including cell-cell fusion. Recent evidence implicates three ADAMs, fertilin-alpha, fertilin-beta, and meltrin-alpha, in sperm-egg fusion and myoblast fusion.
Ari Pekka J Huovila, Judith M. White, Eduardo Ac Almeida   +2 more
openaire   +3 more sources

Eukaryotic Cell–Cell Fusion Families

2011
Abstract The capacity of cells to unite in a regulated fashion, through fusion of their plasma membranes, is essential for reproduction and development in eukaryotes. Yet, the majority of proteins that mediate this process (i.e. fusogens) remain unidentified or uncharacterized.
Ori Avinoam, Benjamin Podbilewicz
openaire   +3 more sources

Signal for cell fusion

Nature, 1976
THE mating of the gametes of Ulva mutabilis1 occurs essentially as described for Chlamydomonas2,3 When the gametes are mixed, they cluster and agglutinate with the tips of their flagella. Pairs consisting of a (+) and (−)-gamete leave the cluster, the cell bodies are brought together and fusion initiated.
Arne Løvlie, Eva Bryhni
openaire   +3 more sources

Biomechanics of virus-to-cell and cell-to-cell fusion

Journal of Biomedical Engineering, 1984
A biomechanical model of virus-to-cell and cell-to-cell fusion is presented. Virus and the cells are modelled as initially spherical membranes of nonlinear elastic material that undergo large deformations. The membranes are connected by a cytoplasmic bridge which expands, resulting in the formation of a larger single sphere.
openaire   +3 more sources

Cell Fusion and Stem Cells

2010
Differentiation, self-renewal and the ability to readily undergo cell fusion are properties of adult and embryonic stem cells. Spontaneous fusion between stem cells, and fusion of stem cells with various differentiated cell types, has been observed in many in vitro and in vivo contexts.
Melissa H. Wong, Paige S. Davies, Anne E. Powell, Alain Silk   +3 more
openaire   +2 more sources

Virus and cell fusion mechanisms.

Annual Review of Cell and Developmental Biology, 2014
In biomembrane fusion pathways, membranes are destabilized through insertions of amphipathic protein segments, lipid reorganization via hemifusion, protein restructuring, and dimpling of the membranes. Four classes of membrane proteins are known in virus
B. Podbilewicz
semanticscholar   +1 more source

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

European Journal of Immunology, 1976
Cell fusion techniques have been used to produce hybrids between myeloma cells and antibody‐producing cells. The hybrid lines derived are permanently adapted to grow in tissue culture and are capable of inducing antibody‐producing tumors in mice.
G. Köhler, C. Milstein
semanticscholar   +1 more source

Cell cycle of multinucleate cells after cell fusion

Experimental Cell Research, 1971
Summary The cell cycle of binucleate and multinucleate cells was studied after fusion of synchronized cells. A prolongation of the S phase in the nuclei of the binucleate cells was observed. Mitosis was not always synchronized in the homokaryons. The duration of the G1 phase in binucleate S/G1 cells is shortened.
A. Westerveld, Maria A. Freeke
openaire   +3 more sources

The dark side of stem cells: triggering cancer progression by cell fusion.

Current molecular medicine, 2013
The phenomenon of cell fusion plays a crucial role in a plethora of physiological processes, including fertilization, wound healing, and tissue regeneration.
T. Dittmar, C. Nagler, B. Niggemann, K. Zänker   +3 more
semanticscholar   +1 more source

Cell fusion is a potent inducer of aneuploidy and drug resistance in tumor cell/ normal cell hybrids.

Critical reviews in oncogenesis, 2013
The biological phenomenon of cell fusion is involved in several physiological (fertilization, tissue regeneration) and pathophysiological (viral infection, cancer) processes.
Benjamin Berndt, K. Zänker, T. Dittmar
semanticscholar   +1 more source