Results 141 to 150 of about 619,300 (360)
Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient Cells [PDF]
, 2022 Jesse D. Champion +13 more
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11LBA Cell reprogramming by hypoxia
European Journal of Cancer Supplements, 2009 Background: Low oxygen tension (hypoxia) is an important determinant in tumor progression. In this study we assess the prognostic value of an in vitro derived hypoxia gene signature in neuroblastoma patients. Material and Methods: L1-L2 regularization framework has been applied on gene expression profiles of 11 neuroblastoma cell lines to define the ...
L. Varesio +5 more
openaire +1 more source
Redox signaling during hypoxia in mammalian cells
Redox Biology, 2017 Hypoxia triggers a wide range of protective responses in mammalian cells, which are mediated through transcriptional and post-translational mechanisms. Redox signaling in cells by reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) occurs through the reversible oxidation of cysteine thiol groups, resulting in structural modifications that ...
Kimberly A. Smith +2 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi +7 more
wiley +1 more source
Cardiology Research and Practice, 2019 Objective. MiR-133b was dysregulated in myocardial infarction. However, the role and mechanism of miR-133b in myocardial infarction remains unclear.
Yongmei Zhou, Hui Huang, Xiaolin Hou
doaj +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Background Myocardial ischemia is the main reason for ischemic heart disease. Baicalin is a plant-derived flavonoid with cardio-protective activity.
Hailiang Yu, Bin Chen, Qi Ren
doaj +1 more source
Glutamate Uptake Is Not Impaired by Hypoxia in a Culture Model of Human Fetal Neural Stem Cell-Derived Astrocytes [PDF]
, 2022 Vadanya Shrivastava +11 more
openalex +1 more source
Advanced Functional Materials, EarlyView.ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Scientific Reports, 2018 Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion.
Céline Hoffmann +10 more
doaj +1 more source