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Apoptotic Cell Death Under Hypoxia
Physiology, 2014Eukaryotic life depends largely on molecular oxygen. During evolution, ingenious mechanisms have evolved that allow organisms to adapt when oxygen levels decrease. Many of these adaptional responses to low oxygen are orchestrated by the heterodimeric transcription factor hypoxia-inducible factor (HIF). Here, we review the link between HIF and apoptosis.
Sendoel Ataman, Hengartner Michael O
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Intermittent hypoxia: cell to system
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2001This symposium was organized to present research dealing with the effects of intermittent hypoxia on cardiorespiratory systems and cellular mechanisms. The pattern of neural impulse activity has been shown to be critical in the induction of genes in neuronal cells and involves distinct signaling pathways.
N R, Prabhakar +3 more
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Cerebral cell population under hypoxia
The Anatomical Record, 1966AbstractThree pregnant albino Sprague‐Dawley rats were subjected to simulated high altitudes of 18,000 feet (365 mm Hg) in low pressure chambers during their entire pregnancy. The brains of the newborn rats were removed immediately after birth and placed in 10% formalin.
R R, Shivers, P G, Roofe
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