Results 181 to 190 of about 349,615 (316)

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal IschemiaIn Vivoand to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis [PDF]

, 2000
Mark P. Mattson, Haiyan Zhu, Jin Yu, Mark S. Kindy   +3 more
openalex   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source

Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability

, 1998
N. M. Hasan, GE Adams, M. C. Joiner, John F. Marshall, IR Hart   +4 more
openalex   +2 more sources

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

Effect of hypoxia duration on the oxygen-dependent production of a recombinant protein, β-galactosidase, by an animal cell line, F6D2, with a hypoxia-inducible enhancer.

, 1997
Yoshihito Shirai, Mikio Inagaki, Masaaki Yamaguchi, Taiho Kambe, Masaya Nagao, Seiji Masuda, Ryuzo Sasaki   +6 more
openalex   +2 more sources

Granular Hydrogels as Brittle Yield Stress Fluids

Advanced Materials, EarlyView.
This work reports the Kamani‐Donley‐Rogers yield stress fluid model can describe granular hydrogel deformation. The model robustly captures transient rheology and self‐healing behavior for granular gels of varying composition using only six parameters. This framework provides new insight regarding the effect of material parameters on granular yielding ...
Gunnar B. Thompson, Jiye Lee, Krutarth M. Kamani, Noah Flores‐Velasco, Simon A. Rogers, Brendan A. C. Harley   +5 more
wiley   +1 more source

Hypoxia stimulates proximal tubular cell matrix production via a TGF-β1-independent mechanism

, 1997
C. Orphanides, Leon G. Fine, Jill T. Norman   +2 more
openalex   +1 more source

Hypoxia and interleukin-1β stimulate vascular endothelial growth factor production in human proximal tubular cells [PDF]

, 2000
Baha El Awad, Burkhard Kreft, Eva-Maria Wolber, Thomas Hellwig‐Bürgel, Eric Metzen, Joachim Fandrey, Wolfgang Jelkmann   +6 more
openalex   +1 more source

Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance

Advanced Materials, EarlyView.
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee, Heung Jin Jeon, Dohyub Jang, Deukhee Lee, Solbi Kim, Minju Han, Sharon Jiyoon Jung, Jung‐Hyun Lee, Jia Choi, Dong Ha Kim, Dong June Ahn, Keri Kim, Sehoon Kim, Hyo‐Jin Lee, SeungBeum Suh   +14 more
wiley   +1 more source