Results 191 to 200 of about 349,615 (316)

Hypoxia Induces Transcription of the Plasminogen Activator Inhibitor-1 Gene Through Genistein-Sensitive Tyrosine Kinase Pathways in Vascular Endothelial Cells [PDF]

open access: bronze, 2000
Tsuyoshi Uchiyama   +8 more
openalex   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

open access: yesAdvanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma   +9 more
wiley   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels   +7 more
wiley   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

open access: yesAdvanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar   +13 more
wiley   +1 more source

UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment. [PDF]

open access: yesCell Death Dis
Suwa T   +10 more
europepmc   +1 more source

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