Deciphering hypoxia's role in hepatocellular carcinoma prognosis with single-cell approaches. [PDF]
Liang J, Chen D, Liang H.
europepmc +1 more source
Hypoxia Induces Transcription of the Plasminogen Activator Inhibitor-1 Gene Through Genistein-Sensitive Tyrosine Kinase Pathways in Vascular Endothelial Cells [PDF]
Tsuyoshi Uchiyama+8 more
openalex +1 more source
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma+9 more
wiley +1 more source
Hypoxia-mediated HES4 promotes the proliferation and motility of hepatocellular carcinoma cell by enhancing COL4A2 transcription. [PDF]
Zhao P, Xu H.
europepmc +1 more source
Hypoxia up-regulates angiopoietin-2, a Tie-2 ligand, in mouse mesangial cells [PDF]
Hai Tao Yuan+2 more
openalex +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels+7 more
wiley +1 more source
Hypoxia/Reoxygenation Stimulates Intracellular Calcium Oscillations in Human Aortic Endothelial Cells [PDF]
Qinghua Hu, Roy C. Ziegelstein
openalex +1 more source
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar+13 more
wiley +1 more source
UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment. [PDF]
Suwa T+10 more
europepmc +1 more source