Results 181 to 190 of about 1,118,590 (267)

Synergistic anticancer effect of ellagic acid and Kaempferol combination in a mouse model of breast cancer. [PDF]

Front Oncol
Shihab RJ, Alasmari MM, Alshaeri HK, Hock M, Talib WH, Ostojic S.   +5 more
europepmc   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Immunological consequences of chemotherapy: implications for cancer immunotherapy. [PDF]

J Immunother Cancer
Bishara GG, Umphred-Wilson K, Abrams SI, Ohm JE, Olejniczak SH.   +4 more
europepmc   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer. [PDF]

Cell Rep Med
Zeng PYF, Meens J, Karimi AH, Pan H, Cecchini MJ, Jarycki L, Ryan SB, Dawson AE, Shaikh MH, Palma DA, Winquist E, Gunaratnam L, Mymryk JS, Barrett JW, Boutros PC, Ailles L, Nichols AC.   +16 more
europepmc   +1 more source

Cadonilimab in the treatment of advanced metastatic soft tissue clear cell sarcoma achieved complete remission: a case report. [PDF]

Front Oncol
Wang Y, Wang X, Meng M, Bai Y, Ma H, He S.   +5 more
europepmc   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Rescue by radiotherapy and anti-CTLA4/PD-1 after failure of anti-PD-1 therapy in patients with metastatic NSCLC: the phase II RECLAIM trial. [PDF]

J Immunother Cancer
Ulas EB, Purcell ND, Houda I, Hashemi SMS, Veltman J, Daniels JMA, Fransen MF, Radonic T, Beeloo LR, van Rossum PSN, van Maldegem F, Barlo N, Disselhorst M, van Laren M, Tiemessen MA, Tarasevych S, van Haarst JM, van Tilburg P, Kunst PWA, Moons-Pasic A, Oprea-Lager DE, Meijboom LJ, Bouwhuis N, de Gruijl TD, Senan S, Schneiders FL, Bahce I.   +26 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source