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Activity of Sulfonium Bisphosphonates on Tumor Cell Lines [PDF]
Journal of Medicinal Chemistry, 2007 We investigated three series of sulfonium bisphosphonates for their activity in inhibiting the growth of three human tumor cell lines. The first series consisted of 6 cyclic sulfonium bisphosphonates, the most active species having an (average) IC50 of 89 microM.
Kilannin Krysiak +7 more
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Nestin expression in human tumors and tumor cell lines.
Neoplasma, 2010The aim of this review is to summarize current knowledge on nestin expression in human tumors and corresponding tumor cell lines. Nestin belongs to class VI of the intermediate filaments and it is expressed primarily in mammalian nervous tissue during embryonic development. In adults, nestin occurs only in a small subset of cells and tissues.
Renata Veselská +3 more
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dbl Oncogene Expression in Childhood Tumors and Tumor Cell Lines
Diagnostic Molecular Pathology, 1993We studied the expression of the dbl oncogene in the total RNA obtained from a wide spectrum of childhood tumors, including Ewing's sarcomas, peripheral neuroectodermal tumors (PNET), esthesioneuroblastomas, neuroblastomas, retinoblastomas, rhabdomyosarcomas, osteosarcomas, and synovial sarcomas.
Antonio Llombart-Bosch +6 more
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, 2005
Despite improvements in survival for pediatric patients with cancer, for those with recurrent, high risk Ewing’s sarcoma (ES) or neuroblastoma (NB) treatment options are limited. Tumor-specific antigens in these malignancies are poorly characterized, and
K. Lucas, J. Mierski, J. Kullen, Qi Sun
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Despite improvements in survival for pediatric patients with cancer, for those with recurrent, high risk Ewing’s sarcoma (ES) or neuroblastoma (NB) treatment options are limited. Tumor-specific antigens in these malignancies are poorly characterized, and
K. Lucas, J. Mierski, J. Kullen, Qi Sun
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Establishment of Tumor Cell Lines: From Primary Tumor Cells to a Tumor Cell Line
2018Adequate cell lines and cell systems are the cornerstone of various research fields, with the aim of reflecting the tissue of origin as closely as possible in order to obtain optimal research conditions. Cell lines are defined as continuously growing cell cultures, with unlimited proliferation.
Beate Rinner, Katharina Meditz
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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.
Science, 1992The doxorubicin-selected lung cancer cell line H69AR is resistant to many chemotherapeutic agents. However, like most tumor samples from individuals with this disease, it does not overexpress P-glycoprotein, a transmembrane transport protein that is ...
S. Cole +9 more
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Development of tumor cell lines
Cancer Genetics and Cytogenetics, 1986A number of techniques are now in use in attempting to establish cell lines from human solid tumors. Although short-term cultures are readily attained, relatively few become established as permanent cell lines, especially from primary carcinomas where metastasis has not already occurred and from such organs as the breast, prostate, and pancreas.
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, 2017
The most important problem with radiotherapy is the limitation of whole body irradiation of a metastatic patient. There are evidence showing that similar effect will occur in non-irradiated tumors similar to the irradiated ones.
H. Zarei +4 more
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The most important problem with radiotherapy is the limitation of whole body irradiation of a metastatic patient. There are evidence showing that similar effect will occur in non-irradiated tumors similar to the irradiated ones.
H. Zarei +4 more
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Human pituitary tumors with two cell lines
Archives of Oto-Rhino-Laryngology, 1983From the total material of 47 pituitary tumors, 42 had one cell line and five had two cell lines. The latter were found in tumors causing acromegaly either with secretion of growth hormone (GH) alone (n = 2) or in combination with prolactin (PRL) (n = 3).
Bernhard Tribukait +2 more
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Resistance of human tumor cell lines to antifolates
Cancer Treatment Reviews, 1984Folate antagonists have over the last 30 years become increasingly important in the treatment of human cancer ( 18). However, only one of these agents, Methotrexate (MTX), can be considered as established in clinical use. Its use in chemotherapy of solid tumors and in maintenance therapy of lymphoblastic leukemia is widespread (12).
Dietrich Niethammer +2 more
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