Results 141 to 150 of about 5,732,679 (357)

Author Correction: Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue

open access: yesScientific Data, 2023
Soon-Chan Kim   +10 more
doaj   +1 more source

Immuno‐Localization of DEAD Family Proteins in Germ Line Cells of Xenopus Embryos. [PDF]

open access: bronze, 1992
Masanao Watanabe   +5 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Phosphoproteomic Analysis of AML14.3D10 Cell Line as a Model System of Eosinophilia [PDF]

open access: gold, 2007
Su-In Ryu   +10 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Real-World Use of Systemic Anticancer Treatment by Histology and Line of Therapy in U.S. Medicare Patients With Advanced Non-Small Cell Lung Cancer [PDF]

open access: bronze, 2014
Lucinda Orsini   +10 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Optimization of a Cav1.2 Cell Line for Use on QPatch and PatchXpress [PDF]

open access: bronze, 2010
Ruth L. Martin   +7 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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