Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Causal models and prediction in cell line perturbation experiments. [PDF]
Long JP+4 more
europepmc +1 more source
e-7. Experimental Brain Tumor Format on after Transplantation of Glia Cell-line
Hideyasu KOMIYA+3 more
openalex +2 more sources
Human T lymphocyte cell line producing colony-stimulating activity [PDF]
DW Golde, S QUAN, MJ Cline
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TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Establishment and characterization of a novel immortalized human aortic valve interstitial cell line. [PDF]
Wang Z, Rao Z, Wang Y, Dong N.
europepmc +1 more source
Re-examination of Growth-promoting Nutrients for L Line Cells in Serum-free Medium
Isao Yamane, Hidenori Koyama
openalex +2 more sources
Growth of Enveloped RNA Viruses in a Line of Chinese Hamster Ovary Cells with Deficient N -Acetyl-glucosaminyltransferase Activity [PDF]
Sondra Schlesinger+4 more
openalex +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Establishment and characterization of CHC-X1: the third human combined hepatocellular-cholangiocarcinoma cell line. [PDF]
Tang H+11 more
europepmc +1 more source