Results 1 to 10 of about 14,505,916 (259)

A novel in vitro system of supported planar endosomal membranes (SPEMs) reveals an enhancing role for cathepsin B in the final stage of Ebola virus fusion and entry

open access: yesMicrobiology Spectrum, 2023
Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycoprotein (GP) is ...
Laura Odongo   +4 more
doaj   +1 more source

The Cell Wall, Cell Membrane and Virulence Factors of Staphylococcus aureus and Their Role in Antibiotic Resistance

open access: yesMicroorganisms, 2023
Antibiotic resistant strains of bacteria are a serious threat to human health. With increasing antibiotic resistance in common human pathogens, fewer antibiotics remain effective against infectious diseases.
Philip Nikolic, Poonam Mudgil
semanticscholar   +1 more source

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

open access: yesNature Communications, 2021
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive nanomedical tools because of their unique properties such as immune escape, long blood circulation time, specific molecular recognition and cell targeting.
Lizhi Liu   +8 more
semanticscholar   +1 more source

Cell membrane coated-nanoparticles for cancer immunotherapy

open access: yesActa Pharmaceutica Sinica B, 2022
Cancer immunotherapy can effectively inhibit cancer progression by activating the autoimmune system, with low toxicity and high effectiveness. Some of cancer immunotherapy had positive effects on clinical cancer treatment.
Yingping Zeng   +5 more
semanticscholar   +1 more source

Cell membrane-coated nanoparticles: a novel multifunctional biomimetic drug delivery system

open access: yesDrug Delivery and Translational Research, 2022
Recently, nanoparticle-based drug delivery systems have been widely used for the treatment, prevention, and detection of diseases. Improving the targeted delivery ability of nanoparticles has emerged as a critical issue that must be addressed as soon as ...
Hui Liu   +3 more
semanticscholar   +1 more source

Reproducible reformation of a bilayer lipid membrane using microair bubbles

open access: yesDroplet, 2023
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto   +6 more
doaj   +1 more source

Cell membranes resist flow [PDF]

open access: yesCell, 2018
SUMMARYThe fluid-mosaic model posits a liquid-like plasma membrane, which can flow in response to tension gradients. It is widely assumed that membrane flow transmits local changes in membrane tension across the cell in milliseconds. This conjectured signaling mechanism has been invoked to explain how cells coordinate changes in shape, motility, and ...
Shi, Zheng   +4 more
openaire   +2 more sources

Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery

open access: yesInternational Journal of Molecular Sciences, 2022
Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of naturally derived design cues for surface modification of nanoparticles.
Na-Hyun Lee   +4 more
semanticscholar   +1 more source

Cell Membrane-Coated Mimics: A Methodological Approach for Fabrication, Characterization for Therapeutic Applications, and Challenges for Clinical Translation

open access: yesACS Nano, 2021
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell membrane and a template of choice to mimic the functions of a cell. The design exploits its physicochemical and biological properties for therapeutic applications.
Vaishali Chugh   +2 more
semanticscholar   +1 more source

Cell membrane-derived vesicles for delivery of therapeutic agents

open access: yesActa Pharmaceutica Sinica B, 2021
Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesicles
Quoc-Viet Le   +4 more
semanticscholar   +1 more source

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