Results 1 to 10 of about 15,080,600 (404)
Microbiology Spectrum, 2023 Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycoprotein (GP) is ...
Laura Odongo +4 more
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Cell membrane-coated nanoparticles: a novel multifunctional biomimetic drug delivery system
Drug Delivery and Translational Research, 2022 Recently, nanoparticle-based drug delivery systems have been widely used for the treatment, prevention, and detection of diseases. Improving the targeted delivery ability of nanoparticles has emerged as a critical issue that must be addressed as soon as ...
Hui Liu +3 more
semanticscholar +1 more source
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
Nature Communications, 2021 Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive nanomedical tools because of their unique properties such as immune escape, long blood circulation time, specific molecular recognition and cell targeting.
Lizhi Liu +8 more
semanticscholar +1 more source
Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery
International Journal of Molecular Sciences, 2022 Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of naturally derived design cues for surface modification of nanoparticles.
Na-Hyun Lee +4 more
semanticscholar +1 more source
Reproducible reformation of a bilayer lipid membrane using microair bubbles
Droplet, 2023 Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto +6 more
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Science Advances, 2021 Genetically engineered cell membrane–coated nanoparticles enable targeted drug delivery to sites of inflammation. As numerous diseases are associated with increased local inflammation, directing drugs to the inflamed sites can be a powerful therapeutic ...
J. Park +8 more
semanticscholar +1 more source
ACS Nano, 2021 Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell membrane and a template of choice to mimic the functions of a cell. The design exploits its physicochemical and biological properties for therapeutic applications.
Vaishali Chugh +2 more
semanticscholar +1 more source
Membrane engineering of cell membrane biomimetic nanoparticles for nanoscale therapeutics
Clinical and Translational Medicine, 2021 In recent years, cell membrane camouflaging technology has emerged as an important strategy of nanomedicine, and the modification on the membranes is also a promising approach to enhance the properties of the nanoparticles, such as cancer targeting ...
Minghai Zhang +4 more
semanticscholar +1 more source
Nature Communications, 2022 Developing antibacterial agents which don’t have cytotoxic effects against mammalian cells is of interest for biomedical applications. Here, the authors explore how attaching inert polymer brushes to different sized nanoparticles can result in toxicity ...
Yunjiang Jiang +6 more
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Malaria Journal, 2020 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika +4 more
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