Results 1 to 10 of about 1,506,215 (109)

A novel in vitro system of supported planar endosomal membranes (SPEMs) reveals an enhancing role for cathepsin B in the final stage of Ebola virus fusion and entry

Microbiology Spectrum, 2023
Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycoprotein (GP) is ...
Laura Odongo, Betelihem H. Habtegebrael, Volker Kiessling, Judith M. White, Lukas K. Tamm   +4 more
doaj   +1 more source

Reproducible reformation of a bilayer lipid membrane using microair bubbles

Droplet, 2023
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto, Toshihisa Osaki, Hirotaka Sugiura, Hisatoshi Mimura, Sho Takamori, Norihisa Miki, Shoji Takeuchi   +6 more
doaj   +1 more source

Hydrophilic nanoparticles that kill bacteria while sparing mammalian cells reveal the antibiotic role of nanostructures

Nature Communications, 2022
Developing antibacterial agents which don’t have cytotoxic effects against mammalian cells is of interest for biomedical applications. Here, the authors explore how attaching inert polymer brushes to different sized nanoparticles can result in toxicity ...
Yunjiang Jiang, Wan Zheng, Keith Tran, Elizabeth Kamilar, Jitender Bariwal, Hairong Ma, Hongjun Liang   +6 more
doaj   +1 more source

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

Malaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika, Alida R. Harahap, Lydia V. Panggalo, Sri Widia A. Jusman, Ari W. Satyagraha   +4 more
doaj   +1 more source

Efficient Lipid Bilayer Formation by Dipping Lipid-Loaded Microperforated Sheet in Aqueous Solution

Micromachines, 2021
This paper describes a method for a bilayer lipid membrane (BLM) formation using a perforated sheet along with an open chamber. Microscopic observation of the formed membrane showed a typical droplet interface bilayer.
Nobuo Misawa, Satoshi Fujii, Koki Kamiya, Toshihisa Osaki, Shoji Takeuchi   +4 more
doaj   +1 more source

Real-time monitoring of proton exchange membrane fuel cell stack failure [PDF]

, 2016
Uneven pressure drops in a 75-cell 9.5-kWe proton exchange membrane fuel cell stack with a U-shaped flow configuration have been shown to cause localised flooding.
Brandon, NP, De Benedetti, L, Marquis, AJ, Offer, GJ, Parkes, MP, Wu, B   +5 more
core   +2 more sources

Automated Segmentation of Cells with IHC Membrane Staining [PDF]

, 2011
This study presents a fully automated membrane segmentation technique for immunohistochemical tissue images with membrane staining, which is a critical task in computerized immunohistochemistry (IHC).
Acquaviva, Andrea, Di Cataldo, Santa, Ficarra, Elisa, Macii, Enrico   +3 more
core   +1 more source

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

Molecular Systems Biology, 2012
The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia, Germaine Goh, Victor Racine, Susanne Ng, Pankaj Kumar, Frederic Bard   +5 more
doaj   +1 more source

Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains

Journal of Lipid Research, 2005
We have recently shown that two ATP binding cassette (ABC) transporters are enriched in Lubrol-resistant noncaveolar membrane domains in multidrug-resistant human cancer cells [Hinrichs, J. W. J., K. Klappe, I. Hummel, and J. W. Kok. 2004.
John W.J. Hinrichs, Karin Klappe, Manon van Riezen, Jan W. Kok   +3 more
doaj   +1 more source

Human hepatic cell behavior on polysulfone membrane with double porosity level [PDF]

, 2013
In the membrane-based bioartificial livers developed up to now,the hepatic cells were located either in the fibers lumen or in the cartridge,with limited capacity for cell hosting.Here,we designed a polysulfone (PSU) membrane with a double porosity ...
Adrianus, Gerard Nathanael, Aimar, Pierre, Bacchin, Patrice, Cerino, Giulia, Dufresne, Murielle, Legallais, Cécile, Remigy, Jean-Christophe   +6 more
core   +2 more sources