Results 1 to 10 of about 15,034,981 (403)

A novel in vitro system of supported planar endosomal membranes (SPEMs) reveals an enhancing role for cathepsin B in the final stage of Ebola virus fusion and entry

open access: yesMicrobiology Spectrum, 2023
Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycoprotein (GP) is ...
Laura Odongo   +4 more
doaj   +1 more source

Biomechanics of Cell Membrane [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
This Special Issue is focused on measuring and characterizing the mechanical and adhesive properties of cells and membranes [...]
Stefano Leporatti, José L. Toca-Herrera
openaire   +3 more sources

Cell membrane-coated nanoparticles: a novel multifunctional biomimetic drug delivery system

open access: yesDrug Delivery and Translational Research, 2022
Recently, nanoparticle-based drug delivery systems have been widely used for the treatment, prevention, and detection of diseases. Improving the targeted delivery ability of nanoparticles has emerged as a critical issue that must be addressed as soon as ...
Hui Liu   +3 more
semanticscholar   +1 more source

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

open access: yesNature Communications, 2021
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive nanomedical tools because of their unique properties such as immune escape, long blood circulation time, specific molecular recognition and cell targeting.
Lizhi Liu   +8 more
semanticscholar   +1 more source

Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery

open access: yesInternational Journal of Molecular Sciences, 2022
Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of naturally derived design cues for surface modification of nanoparticles.
Na-Hyun Lee   +4 more
semanticscholar   +1 more source

Reproducible reformation of a bilayer lipid membrane using microair bubbles

open access: yesDroplet, 2023
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto   +6 more
doaj   +1 more source

Genetically engineered cell membrane–coated nanoparticles for targeted delivery of dexamethasone to inflamed lungs

open access: yesScience Advances, 2021
Genetically engineered cell membrane–coated nanoparticles enable targeted drug delivery to sites of inflammation. As numerous diseases are associated with increased local inflammation, directing drugs to the inflamed sites can be a powerful therapeutic ...
J. Park   +8 more
semanticscholar   +1 more source

Cell Membrane-Coated Mimics: A Methodological Approach for Fabrication, Characterization for Therapeutic Applications, and Challenges for Clinical Translation

open access: yesACS Nano, 2021
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell membrane and a template of choice to mimic the functions of a cell. The design exploits its physicochemical and biological properties for therapeutic applications.
Vaishali Chugh   +2 more
semanticscholar   +1 more source

Membrane engineering of cell membrane biomimetic nanoparticles for nanoscale therapeutics

open access: yesClinical and Translational Medicine, 2021
In recent years, cell membrane camouflaging technology has emerged as an important strategy of nanomedicine, and the modification on the membranes is also a promising approach to enhance the properties of the nanoparticles, such as cancer targeting ...
Minghai Zhang   +4 more
semanticscholar   +1 more source

Hydrophilic nanoparticles that kill bacteria while sparing mammalian cells reveal the antibiotic role of nanostructures

open access: yesNature Communications, 2022
Developing antibacterial agents which don’t have cytotoxic effects against mammalian cells is of interest for biomedical applications. Here, the authors explore how attaching inert polymer brushes to different sized nanoparticles can result in toxicity ...
Yunjiang Jiang   +6 more
doaj   +1 more source

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