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Microbiology Spectrum, 2023 Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycoprotein (GP) is ...
Laura Odongo +4 more
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Biomechanics of Cell Membrane [PDF]
International Journal of Molecular Sciences, 2020 This Special Issue is focused on measuring and characterizing the mechanical and adhesive properties of cells and membranes [...]
Stefano Leporatti, José L. Toca-Herrera
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Reproducible reformation of a bilayer lipid membrane using microair bubbles
Droplet, 2023 Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto +6 more
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Nature Communications, 2022 Developing antibacterial agents which don’t have cytotoxic effects against mammalian cells is of interest for biomedical applications. Here, the authors explore how attaching inert polymer brushes to different sized nanoparticles can result in toxicity ...
Yunjiang Jiang +6 more
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Malaria Journal, 2020 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika +4 more
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Electroporation of cell membranes [PDF]
Biophysical Journal, 1989 Electric pulses of intensity in kilovolts per centimeter and of duration in microseconds to milliseconds cause a temporary loss of the semipermeability of cell membranes, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
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Efficient Lipid Bilayer Formation by Dipping Lipid-Loaded Microperforated Sheet in Aqueous Solution
Micromachines, 2021 This paper describes a method for a bilayer lipid membrane (BLM) formation using a perforated sheet along with an open chamber. Microscopic observation of the formed membrane showed a typical droplet interface bilayer.
Nobuo Misawa +4 more
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RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells
Molecular Systems Biology, 2012 The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia +5 more
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Journal of Lipid Research, 2005 We have recently shown that two ATP binding cassette (ABC) transporters are enriched in Lubrol-resistant noncaveolar membrane domains in multidrug-resistant human cancer cells [Hinrichs, J. W. J., K. Klappe, I. Hummel, and J. W. Kok. 2004.
John W.J. Hinrichs +3 more
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In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties
Nature Communications, 2019 Regulated exocytosis of neuronal synaptic vesicles is substantially faster than that of endocrine dense core vesicles despite similar molecular machineries.
Alex J. B. Kreutzberger +10 more
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