Results 1 to 10 of about 8,204,422 (306)

Therapy-induced senescence in breast cancer: an overview

Exploration of Targeted Anti-tumor Therapy
Outcomes for women with breast cancer have improved dramatically in recent decades. However, many patients present with intrinsic drug resistance and others are initially sensitive to anti-cancer drugs but acquire resistance during the course of their ...
Suraj Narayanan Chembukavu, Andrew J Lindsay   +1 more
doaj   +1 more source

Multilayered regulation of GluK3 kainate receptors is mediated by Neto subunits and zinc

Communications Biology
Kainate receptors (KARs), a distinct subfamily of ionotropic glutamate receptors, are critical modulators of synaptic transmission and network excitability. Their function is intricately regulated by auxiliary subunits and endogenous ions.
Rajesh Vinnakota, Bhavya K. Dawath, Anshul Assaiya, Suparna Bhar, Janesh Kumar   +4 more
doaj   +1 more source

Cornichons: Evolution, AMPA receptor modulation, and emerging roles beyond the nervous system

Brain Disorders
Cornichons are auxiliary proteins that regulate the functions of AMPA receptors (AMPARs), which mediate fast excitatory transmission in the central nervous system.
Pratibha Bharti, Anshul Assaiya, Bhavya K Dawath, Janesh Kumar   +3 more
doaj   +1 more source

A systematic computational analysis of the endosomal recycling pathway in glioblastoma

Biochemistry and Biophysics Reports
Glioblastoma (GBM) is the most common and aggressive brain cancer in adults. The standard treatment is brutal and has changed little in 20 years, and more than 85% of patients will die within two years of their diagnosis.
Luke J. Joyce, Andrew J. Lindsay
doaj   +1 more source

Partitioning to ordered membrane domains regulates the kinetics of secretory traffic

eLife
The organelles of eukaryotic cells maintain distinct protein and lipid compositions required for their specific functions. The mechanisms by which many of these components are sorted to their specific locations remain unknown. While some motifs mediating
Ivan Castello-Serrano, Frederick A Heberle, Barbara Diaz-Rohrer, Rossana Ippolito, Carolyn R Shurer, Pablo Lujan, Felix Campelo, Kandice R Levental, Ilya Levental   +8 more
doaj   +1 more source

Expression and Purification of the Human Voltage-Gated Proton Channel (hHv1)

Bio-Protocol
The voltage-gated proton channel (Hv1) is a membrane protein that dissipates acute cell proton accumulations. To understand the molecular mechanisms explaining Hv1 function, methods for purifying the protein are needed. Previously, methods were developed
Emerson Carmona, D. Marien Cortes, Luis Cuello   +2 more
doaj   +1 more source

Are Cell Membranes Fluid? [PDF]

Science, 1973
openaire   +2 more sources

Rotating Membrane Cell [PDF]

Science, 1968
T M, Regan, W G, Esmond, C, Streckfus, A M, Wlbarsht   +3 more
openaire   +2 more sources

Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy. [PDF]

Clin Transl Med
Wu Q, Xue Y, Zhang K, Xu K, Xu T, Fu H, Zhang S, Zhang M, Sun R, Shan Chan SH, Zhou L, Cai X, Guo Y, Xu H.   +13 more
europepmc   +1 more source

A Metal Importer and Exporter Interact Differently in the Chloroplast and Cell Membrane. [PDF]

Membranes (Basel)
Paul K, Ray B, Saha C, Roy A, Basu S, Seal A.   +5 more
europepmc   +1 more source