Results 21 to 30 of about 2,877,371 (319)

Plasma membrane integrity in health and disease: significance and therapeutic potential

open access: yesCell Discovery, 2021
Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane.
Catarina Dias, Jesper Nylandsted
doaj   +1 more source

LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion

open access: yesCell Reports, 2013
During interphase, centrosomes are connected by a proteinaceous linker between the proximal ends of the centrioles, which is important for the centrosomes to function as a single microtubule-organizing center.
Runsheng He   +5 more
doaj   +1 more source

Effects of membrane alterations on bacterial retention [PDF]

open access: yes, 2010
The study shows the respective roles of skin and support of an ultrafiltration membrane in the retention mechanisms of bacteria (Escherichia coli).
Causserand, Christel   +3 more
core   +1 more source

The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis

open access: yesNature Communications, 2020
ESCRT filaments drive the final abscission between two daughter cells but how they physically interact with the membrane is unclear. Using proteomics, the authors show that syndecan-4/syntenin/ALIX couples the ESCRT machinery to the abscission site and ...
Cyril Addi   +16 more
doaj   +1 more source

Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo

open access: yesEuropean Journal of Cell Biology, 2022
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must be finely tuned, both in space and time, to fulfill key cellular functions
Clémentine Rouyère   +3 more
doaj   +1 more source

IDEAL-Cell, a High Temperature Innovative Dual mEmbrAne Fuel-Cell

open access: yes, 2009
IDEAL-Cell is a new concept of a high temperature fuel cell operating in the range 600-700°C. It is based on the junction between the anode part of a PCFC and the cathode part of a SOFC through a mixed H+ and O2- conducting porous ceramic membrane.
Stoynov, Z.   +17 more
core   +1 more source

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin

open access: yes, 2004
Copyright © 2004 by The American Society for Cell Biology.Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway.
Murray, Rachael   +11 more
core   +1 more source

Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]

open access: yes, 2008
The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S.   +4 more
core   +1 more source

The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets

open access: yes, 2016
Peptidoglycan is the major component of the cell envelope of virtually all bacteria. It has structural roles and acts as a selective sieve for molecules from the outer environment. Peptidoglycan synthesis is therefore one of the most important biogenesis
Eefjan Breukink   +5 more
core   +1 more source

Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion

open access: yesNature Communications, 2016
HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al.
Sung-Tae Yang   +2 more
doaj   +1 more source

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