Results 161 to 170 of about 15,034,981 (403)
Embryonic Membranes, Yolk Cells, and Morphogenesis of the Stonefly Pteronarcys Proteus Newman1, 2 (Plecoptera: Pteronarcidae) [PDF]
Albert J. Miller
openalex +1 more source
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain+3 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
SEMIPERMEABILITY OF THE NUCLEAR MEMBRANE IN THE INTACT CELL [PDF]
Clifford V. Harding, Carl M. Feldherr
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B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
The organelles of eukaryotic cells maintain distinct protein and lipid compositions required for their specific functions. The mechanisms by which many of these components are sorted to their specific locations remain unknown. While some motifs mediating
Ivan Castello-Serrano+8 more
doaj +1 more source
The effect of redox dyes on the active transport of hydrogen, potassium and sodium ions across the yeast cell membrane [PDF]
E. J. Conway, R. P. Kernan
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
Yigong Shi, J. Massagué
semanticscholar +1 more source