Results 51 to 60 of about 14,811,249 (209)
Near-critical fluctuations and cytoskeleton-assisted phase separation lead to subdiffusion in cell membranes [PDF]
Biophysical Journal 100 (2011) 80, 2010 We address the relationship between membrane microheterogeneity and anomalous subdiffusion in cell membranes by carrying out Monte Carlo simulations of two-component lipid membranes. We find that near-critical fluctuations in the membrane lead to transient subdiffusion, while membrane-cytoskeleton interaction strongly affects phase separation, enhances
arxiv +1 more source
Polymer-encased nanodiscs with improved buffer compatibility
Scientific Reports, 2017 Styrene-maleic acid copolymers allow for solubilization and reconstitution of membrane proteins into nanodiscs. These polymer-encased nanodiscs are promising platforms for studies of membrane proteins in a near-physiologic environment without the use of ...
Mariana C. Fiori +3 more
doaj +1 more source
Nature Communications, 2023 Lysosomes communicate through cholesterol transfer at endoplasmic reticulum (ER) contact sites. At these sites, the Niemann Pick C1 cholesterol transporter (NPC1) facilitates the removal of cholesterol from lysosomes, which is then transferred to the ER ...
Maria Casas +7 more
doaj +1 more source
Integrin-mediated membrane blebbing is dependent on the NHE1 and NCX1 activities. [PDF]
, 2011 Integrin-mediated signal transduction and membrane blebbing have been well studied to modulate cell adhesion, spreading and migration^1-6^. However, the relationship between membrane blebbing and integrin signaling has not been explored.
Chi-Hung Lin +8 more
core +1 more source
Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum. [PDF]
, 2019 We previously showed that Entamoeba histolytica kills human cells through a mechanism that we termed trogocytosis ("trogo-" means "nibble"), due to its resemblance to trogocytosis in other organisms. In microbial eukaryotes like E.
Miller, Hannah W +2 more
core +1 more source
A Mathematical Model for Predicting the Life of PEM Fuel Cell Membranes Subjected to Hydration Cycling [PDF]
Journal of Power Sources 215 (2012) 135-144, 2013 Under typical PEM fuel cell operating conditions, part of membrane electrode assembly is subjected to humidity cycling due to variation of inlet gas RH and/or flow rate. Cyclic membrane hydration/dehydration would cause cyclic swelling/shrinking of the unconstrained membrane.
arxiv +1 more source
Drug Delivery, 2019 Efficient cellular delivery of biologically active molecules is one of the key factors that affect the discovery and development of novel drugs. The plasma membrane is the first barrier that prevents direct translocation of chemic entities, and thus ...
Renshuai Zhang +4 more
semanticscholar +1 more source
Functional implications of the exon 9 splice insert in GluK1 kainate receptors
eLifeKainate receptors are key modulators of synaptic transmission and plasticity in the central nervous system. Different kainate receptor isoforms with distinct spatiotemporal expressions have been identified in the brain.
Surbhi Dhingra +3 more
doaj +1 more source
Oxidation of F-actin controls the terminal steps of cytokinesis
Nature Communications, 2017 Cytokinetic abscission relies on the local constriction after cytoskeleton disassembly, but it is not known how the actin filaments are disassembled. Here, the authors show that the redox enzyme MICAL1 is recruited by Rab35 and induces oxidation-mediated
Stéphane Frémont +11 more
doaj +1 more source
TTL-Expression Modulates Epithelial Morphogenesis
Frontiers in Cell and Developmental Biology, 2021 Epithelial monolayer formation depends on the architecture and composition of the microtubule cytoskeleton. Microtubules control bidirectional trafficking and determine the positioning of structural cellular proteins.
Manuel Müller +10 more
doaj +1 more source