Results 61 to 70 of about 3,952,478 (297)

Hysteresis and bi-stability by an interplay of calcium oscillations and action potential firing

open access: yes, 2006
Many cell types exhibit oscillatory activity, such as repetitive action potential firing due to the Hodgkin-Huxley dynamics of ion channels in the cell membrane or reveal intracellular inositol triphosphate (IP$_3$) mediated calcium oscillations (CaOs ...
A. P. R. Theuvenet   +9 more
core   +1 more source

Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]

open access: yes, 2008
The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E   +4 more
core   +1 more source

A finite element method for a fourth order surface equation with application to the onset of cell blebbing [PDF]

open access: yes, 2020
A variational problem for a fourth order parabolic surface partial differential equation is discussed. It contains nonlinear lower order terms, on which we only make abstract assumptions, and which need to be defined for specified problems.We derive a ...
Dedner, Andreas   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Meteoroid capture cell construction [PDF]

open access: yes, 1976
A thin membrane covering the open side of a meteoroid capture cell causes an impacting meteoroid to disintegrate as it penetrates the membrane.
High, R. W., Zook, H. A.
core   +1 more source

The effects of water and microstructure on the performance of polymer electrolyte fuel cells [PDF]

open access: yes, 2006
n this paper, we present a comprehensive non-isothermal, one-dimensional model of the cathode side of a Polymer Electrolyte Fuel Cell. We explicitly include the catalyst layer, gas diffusion layer and the membrane.
A. Young   +59 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole

open access: yesNature Communications, 2018
Ciliogenesis is negatively regulated by the CP110-CEP97 complex, although the mechanism controlling mother centriole localization is poorly understood. Here, Huang et al.
Ning Huang   +6 more
doaj   +1 more source

Fabrication of bifunctional membrane electrode assemblies for unitised regenerative polymer electrolyte fuel cells [PDF]

open access: yes, 2006
Bifunctional membrane electrode assemblies have been fabricated using a screen printing technique, which demonstrate a repeatable and stable operation to cell current and voltages.
Harrison, DJ, Pettersson, J, Ramsey, BJ
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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