Results 71 to 80 of about 7,491,510 (261)

Twisted scroll waves organize Dictyostelium mucoroides slugs [PDF]

, 1997
Cellular slime moulds (Dictyosteloids) are characterised by at least two different modes of slug migration. Most species, e.g. Dictyostelium mucoroides, produce a stalk continuously during slug migration, while a few species, e.g.
Siegert, Florian, Dormann, Dirk, Weijer, Cornelis J.   +2 more
core   +1 more source

Chronic Starvation Stress Promotes Migration Ability of Colorectal Cancer Cells by Inducing ITGB1 Upregulation

Zhongliu Fangzhi Yanjiu
Objective To investigate the effects of chronic starvation stress on the proliferation and migration of colorectal cancer cells, as well as the underlying mechanisms.
LI Siyu, CAO Jinghua, WANG Fengwei
doaj   +1 more source

Progressive adaptation of whole-limb kinematics after peripheral nerve injury

Biology Open, 2018
The ability to recover purposeful movement soon after debilitating neuromuscular injury is essential to animal survival. Various neural and mechanical mechanisms exist to preserve whole-limb kinematics despite exhibiting long-term deficits of individual ...
Young-Hui Chang, Stephen N. Housley, Kerry S. Hart, Paul Nardelli, Richard T. Nichols, Huub Maas, Timothy C. Cope   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Semblance Of heterogeneity in collective cell migration [PDF]

, 2017
Cell population heterogeneity is increasingly a focus of inquiry in biological research. For example, cell migration studies have investigated the heterogeneity of invasiveness and taxis in development, wound healing, and cancer.
Linus J. Schumacher, Philip K. Maini, Ruth E. Baker, Baker, RE, Maini, PK, Schumacher, LJ   +5 more
core   +1 more source

Targeted therapy on glioma migration and invasion

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Malignant glioma, one of the most lethal malignancies, is the most common primary central nervous system tumor with a dismal prognosis. The major obstacle to cure and recurrence is diffuse invasion, which enables glioma cells to escape complete surgical ...
Tao LI, Long HAI, Xue⁃jun YANG
doaj  

Higher Daily Physical Activity Level Is Associated with Lower RBC Aggregation in Carotid Artery Disease Patients at High Risk of Stroke

Frontiers in Physiology, 2017
Aim: Carotid artery disease (CAD) is an atherosclerotic inflammatory disease that affects the arterial wall, specifically at points of bifurcation where blood flow is disturbed. Abnormal blood rheology could participate in the pathophysiology of ischemic
Pauline Mury, Pauline Mury, Camille Faes, Camille Faes, Antoine Millon, Antoine Millon, Mathilde Mura, Mathilde Mura, Céline Renoux, Céline Renoux, Céline Renoux, Sarah Skinner, Sarah Skinner, Virginie Nicaise, Philippe Joly, Philippe Joly, Philippe Joly, Nellie Della Schiava, Patrick Lermusiaux, Philippe Connes, Philippe Connes, Philippe Connes, Vincent Pialoux, Vincent Pialoux, Vincent Pialoux   +24 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A Pilot Study of Botulinum Toxin for Jerky, Position-Specific, Upper Limb Action Tremor

Tremor and Other Hyperkinetic Movements, 2016
Background: We aimed to investigate the efficacy and safety of botulinum toxin (BT) injections for jerky action tremor of the upper limb.Methods: We performed an uncontrolled, prospective study of electromyography (EMG)-guided BT injections for jerky ...
Tabish A. Saifee, Tiago Teodoro, Roberto Erro, Mark J. Edwards, Carla Cordivari   +4 more
doaj   +1 more source