Results 71 to 80 of about 669,615 (306)
Computational Modeling of Single-Cell Migration::The Leading Role of Extracellular Matrix Fibers [PDF]
, 2012 Cell migration is vitally important in a wide variety of biological contexts ranging from embryonic development and wound healing to malignant diseases such as cancer. It is a very complex process that is controlled by intracellular signaling pathways as
Schlüter, Daniela K. +4 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Interplay between intercellular signaling and cell movement in development [PDF]
Cell movement and local intercellular signaling are crucial components of morphogenesis during animal development. Intercellular signaling regulates the collective movement of a cell population via direct cell-cell contact. Cell movement, conversely, can
Oates, A. C., Uriu, K., Morelli, L. G.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Zhongliu Fangzhi YanjiuObjective To investigate the effects of chronic starvation stress on the proliferation and migration of colorectal cancer cells, as well as the underlying mechanisms.
LI Siyu, CAO Jinghua, WANG Fengwei
doaj +1 more source
Biomolecules and Cardiovascular Diseases in Women
Biomolecules, 2022 Although cardiovascular diseases (CVD) are the leading cause of non-communicable diseases-dependent death worldwide, their effects are still largely underestimated in women [...]
Barbara Ghinassi +2 more
doaj +1 more source
Effects of Calreticulin on Viral Cell-to-Cell Movement [PDF]
Plant Physiology, 2005 Abstract Cell-to-cell tobacco mosaic virus movement protein (TMV MP) mediates viral spread between the host cells through plasmodesmata. Although several host factors have been shown to interact with TMV MP, none of them coresides with TMV MP within plasmodesmata.
Min-Huei, Chen +3 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Coupled Excitable Ras and F-actin activation mediate spontaneous pseudopod formation and directed cell movement [PDF]
, 2017 Many eukaryotic cells regulate their mobility by external cues. Genetic studies have identified >100 components that participate in chemotaxis, which hinders the identification of the conceptual framework of how cells sense and respond to shallow ...
Kortholt, Arjan; id_orcid +3 more
core +1 more source
, 2022 S.301-312The introduction of stem cell-associated molecular factors into human patient-derived cells allows for their reprogramming in the laboratory environment.
Müller, F.J. +5 more
core +1 more source