Results 91 to 100 of about 23,513,766 (356)
International Journal of Electrochemical Science, 2012 This paper presents a technique to determine cell number in 3D cell culture construct quantitatively. A measurement platform embedded with on-chip vertical electrodes has been developed and is capable of onsite impedimetric detecting cell number without ...
Kin Fong Lei +3 more
doaj +1 more source
Nature Genetics, 2017 The CRISPR–Cas9 system has revolutionized gene editing both at single genes and in multiplexed loss-of-function screens, thus enabling precise genome-scale identification of genes essential for proliferation and survival of cancer cells.
R. Meyers +29 more
semanticscholar +1 more source
Cell death regulates muscle fiber number
Developmental Biology, 2016 Cell death can have both cell autonomous and non-autonomous roles in normal development. Previous studies have shown that the central cell death regulators grim and reaper are required for the developmentally important elimination of stem cells and neurons in the developing central nervous system (CNS).
Tatevik, Sarkissian +4 more
openaire +2 more sources
Developmental Disorders in Children Recently Diagnosed With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag +5 more
wiley +1 more source
Limitations and possibilities of low cell number ChIP-seq
BMC Genomics, 2012 Background Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq) offers high resolution, genome-wide analysis of DNA-protein interactions. However, current standard methods require abundant starting material in the range of
Gilfillan Gregor D +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source
DNA methylation age of human tissues and cell types
Genome Biology, 2013 It is not yet known whether DNA methylation levels can be used to accurately predict age across a broad spectrum of human tissues and cell types, nor whether the resulting age prediction is a biologically meaningful measure.
S. Horvath
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
cMyc increases cell number through uncoupling of cell division from cell size in CHO cells
BMC Biotechnology, 2009 Background Over the past decades, the increase in maximal cell numbers for the production of mammalian derived biologics has been in a large part due to the development of optimal feeding strategies.
Kuystermans Darrin, Al-Rubeai Mohamed
doaj +1 more source
The roles of cell size and cell number in determining ovariole number in Drosophila
Developmental Biology, 2012 All insect ovaries are composed of functional units called ovarioles, which contain sequentially developing egg chambers. The number of ovarioles varies between and within species. Ovariole number is an important determinant of fecundity and thus affects individual fitness.
Sarikaya, Didem Pelin +5 more
openaire +3 more sources