Results 161 to 170 of about 23,513,766 (356)

Inferring single-cell copy number profiles through cross-cell segmentation of read counts

open access: yesBMC Genomics
Background Copy number alteration (CNA) is one of the major genomic variations that frequently occur in cancers, and accurate inference of CNAs is essential for unmasking intra-tumor heterogeneity (ITH) and tumor evolutionary history.
Furui Liu, Fangyuan Shi, Zhenhua Yu
doaj   +1 more source

Lesional CD8+ T-Cell Number Predicts Surgical Outcomes of Melanocyte-Keratinocyte Transplantation Surgery for Vitiligo. [PDF]

open access: yesJ Invest Dermatol, 2023
Refat MA   +10 more
europepmc   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Chromosomal Number Aberrations and Transformation in Adult Mouse Retinal Stem Cells In Vitro

open access: green, 2009
Meta W. Djojosubroto   +5 more
openalex   +2 more sources

Differential effect of lithium on cell number in the hippocampus and prefrontal cortex in adult mice: a stereological study

open access: yesBipolar Disorders, 2016
G. Rajkowska   +8 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes. [PDF]

open access: yesInt J Mol Sci, 2023
Kothegala L   +4 more
europepmc   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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