Results 91 to 100 of about 124,652 (274)

The growth of sun and shade leaves of Populus euramericana "robusta" in relation to age, light intensity and temperature

, 1974
The growth and development of sun and shade leaves was investigated in Populus euramericana 'Robusta', growing under various light intensities and temperatures and on a substrate optimal for the roots.Strong correlations exist between the dimensions of ...
Pieters, G.A.
core  

Iron metabolism and ferroptosis in human health and disease

BMC Biology
Iron is indispensable to most lifeforms, underpinning a myriad of physiological processes. Dysregulation of iron homeostasis underlies a broad spectrum of biological phenomena and pathological conditions.
Meijuan Zhong, Yuandi Wang, Junxia Min, Fudi Wang   +3 more
doaj   +1 more source

Confined gas transport in low-dimensional materials

International Journal of Smart and Nano Materials
Gas transport under confinement exhibits a plethora of physical and chemical phenomena that differ from those observed in bulk media, owing to the deviations of continuum description at the molecular level.
Hongwei Duan, Zeyu Zhuang, Jing Yang, Shengping Zhang, Luda Wang   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Determinação do metaboloma foliar parcial de variedades crioulas de milho (Zea mays), visando a caracterização dos extratos foliares contendo (poli)fenóis e carotenóides [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Recursos Genéticos Vegetais, Florianópolis, 2010O estabelecimento do perfil metabolômico parcial das folhas de variedades crioulas de ...
Lemos, Priscilla Maria Menel
core  

Hydrodynamics in Cell Studies

, 2018
Hydrodynamic phenomena are ubiquitous in living organisms and can be used to manipulate cells or emulate physiological microenvironments experienced in vivo.
Huber, Deborah, Solvas, Xavier Casadevall I., Xavier Casadevall i Solvas, Oskooei, Ali, Govind V. Kaigala, Casadevall i Solvas, Xavier, deMello, Andrew J., Deborah Huber, Kaigala, Govind V., Ali Oskooei, deMello, Andrew, Andrew deMello   +11 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Benzo-pyrrolidinyl substituted silicon phthalocyanines: A novel two-photon lysosomal nanoprobe for in vitro photodynamic therapy

Photodiagnosis and Photodynamic Therapy
Lysosomes are pivotal in diverse physiological phenomena, encompassing autophagy, apoptosis, and cellular senescence. The demand for precise tumors treatment has led to the development of specific lysosome-targeting probes capable of elucidating ...
Xiuqin Chen, Guizhi Chen, Sitong Cao, Ruoxin Ye, Ruoyi Qiu, Xiangyu Yang, Yiru Peng, Hong Sun   +7 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source