Results 171 to 180 of about 2,032,190 (314)

Genetic recording of pancreatic beta cell proliferation. [PDF]

Proc Natl Acad Sci U S A
Zhao H, Chen H, Kang Z, Huang X, Zhu J, Liu Z, Liu X, Han X, Lu J, Zhou B.   +9 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

SHCBP1 Is Upregulated in Colon Adenocarcinoma and Promotes Tumor Cell Proliferation and Growth. [PDF]

Curr Oncol
He Y, Zhang Q, He X, Wu W.
europepmc   +1 more source

Measurement of cell proliferation

Gastroenterology, 1984
R A, Goodlad, N A, Wright
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Negatively Charged Pronucleotides as Inhibitors of Glioma Cell Proliferation. [PDF]

ACS Med Chem Lett
Romanowska J, Wawrzyniak D, Szymanska-Michalak A, Framski G, Pawlowicz-Perczak A, Sobkowski M, Stawinski J, Rolle K, Kraszewski A.   +8 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Expression of Concern: ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Regulation of Cell Proliferation and Migration by Extracellular Phosphatidic Acid. [PDF]

Biomedicines
Gomez-Larrauri A, Benito-Vicente A, Uribe KB, Martin C, Gomez-Muñoz A.   +4 more
europepmc   +1 more source