Results 211 to 220 of about 809,436 (268)
Emerging roles of amphiregulin in disease pathogenesis and therapeutic promise. [PDF]
iScienceLi N, He J, Liu M, Zha L.
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Clinical value of IL-17-targeted intervention in tissue injury repair: from bidirectional mechanisms to therapeutic strategies. [PDF]
Front ImmunolAn W +8 more
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DNA damage response inhibitors in pancreatic cancer: progress and challenges. [PDF]
Front OncolWu Y, Li W, Wu M.
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Clinics in Chest Medicine, 1981
Occupational lung disease results from a remarkably complex interaction of the inhaled material with the lung parenchyma and the worker's immune and inflammatory mechanism, (Fig 1). The past decade has seen a marked increase in our understanding of individual events involved in the pathogenesis of occupational lung disease, and has seen increased ...
E J, Campbell, R M, Senior
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Occupational lung disease results from a remarkably complex interaction of the inhaled material with the lung parenchyma and the worker's immune and inflammatory mechanism, (Fig 1). The past decade has seen a marked increase in our understanding of individual events involved in the pathogenesis of occupational lung disease, and has seen increased ...
E J, Campbell, R M, Senior
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Current Opinion in Pharmacology, 2006
Advances in the treatment of acute myocardial infarction have led to increased survival but also an increase in those suffering from heart failure. The concept of adult progenitor cell therapy has grown from observations that cardiac function improves after injection of bone marrow-derived cells into infarcted regions in animal models. The mechanism of
Nicholas F, Grigoropoulos +1 more
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Advances in the treatment of acute myocardial infarction have led to increased survival but also an increase in those suffering from heart failure. The concept of adult progenitor cell therapy has grown from observations that cardiac function improves after injection of bone marrow-derived cells into infarcted regions in animal models. The mechanism of
Nicholas F, Grigoropoulos +1 more
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The mechanism of cell membrane repair
Zygote, 1999Disruption of plasma membranes is a widespread, common and normal event that occurs in many mechanically challenged tissues (McNeil & Steinhardt, 1997). After injury to the plasma membrane, rapid resealing of the membrane occurs with little loss of intracellular contents.Analysis of plasma membrane repair in the sea urchin egg and early embryos ...
T, Togo, J M, Alderton, R A, Steinhardt
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Programming cells for cardiac repair
Current Opinion in Biotechnology, 2017Because the heart is a poorly regenerative organ, there has been considerable interest in developing novel cell-based approaches to restore lost contractile function after myocardial infarction (MI). While a wide variety of candidate cell types have been tested in animal MI models, the vast majority of clinical trials have used adult stem cell types ...
Rocco, Romagnuolo, Michael A, Laflamme
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Mismatch repair in mammalian cells
BioEssays, 1990AbstractA vital process in maintaining a low genetic error rate is the removal of mismatched bases in DNA. The importance of this process in E. coli is demonstrated by the 100–1000 fold increase in mutation frequency observed in cells deficient in this repair system(1).
L A, Heywood, J F, Burke
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Stem cells and repair of the heart
The Lancet, 2004Stem-cell therapy provides the prospect of an exciting and powerful treatment to repair the heart. Although research has been undertaken in animals to analyse the safety and efficacy of this new approach, results have been inconclusive. The mechanism by which stem cells could improve cardiac function remains unclear.
A, Mathur, J F, Martin
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