Results 181 to 190 of about 12,492,811 (359)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Therapeatic evaluation and single cell analysis of adipose stromal vascular fraction isolation from a commercial cell separation system. [PDF]

Stem Cell Res Ther
Han S, Zhang Q, Lu F, Cai J.
europepmc   +1 more source

Comparison of Red Blood Cell Hemolysis Using Plasma and Serum Separation Tubes for Outpatient Specimens

, 2015
Dae‐Hyun Ko, Dahae Won, Tae‐Dong Jeong, Woochang Lee, Sail Chun, Won‐Ki Min   +5 more
openalex   +2 more sources

The fission yeast Rpb4 subunit of RNA polymerase II plays a specialized role in cell separation [PDF]

, 2006
Nimisha Sharma, Samuel Marguerat, Surbhi Mehta, Stephen Watt, Jürg Bähler   +4 more
openalex   +1 more source

Label-Free Separation of Circulating Tumor Cells from Red Blood Cells on a Lab-on-A-Foil Microfluidic Device Using Traveling-Wave Dielectrophoresis

, 2022
Mengren Wu, Yuan Gao, Qiyue Luan, Ian Papautsky, Xiaolin Chen, Jie Xu   +5 more
openalex   +1 more source

High-throughput and clogging-free microfluidic filtration platform for on-chip cell separation from undiluted whole blood.

Biomicrofluidics, 2016
Yinuo Cheng, X. Ye, Zengshuai Ma, Shuai Xie, Wenhui Wang   +4 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Fabrication of a new all-in-one microfluidic dielectrophoresis integrated chip and living cell separation. [PDF]

iScience, 2022
Oshiro K, Wakizaka Y, Takano M, Itoi T, Ohge H, Koba K, Yarimizu K, Fujiyoshi S, Maruyama F.   +8 more
europepmc   +1 more source

A role for hilar cells in pattern separation in the dentate gyrus: A computational approach

, 2008
Catherine E. Myers, Helen E. Scharfman
openalex   +1 more source

Separation and Characterization of Prostate Cancer Cell Subtype according to Their Motility Using a Multi-Layer CiGiP Culture [PDF]

, 2018
Linxiang Wang, Ying Zhou, Jingjing Fu, Zhisong Lu, Ling Yu   +4 more
openalex   +1 more source