Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Particle and Cell Separation in Deterministic Lateral Displacement Arrays with Inverse L-Shaped Pillars. [PDF]
Jiang H +4 more
europepmc +1 more source
Polygalacturonase activity promotes aberrant cell separation in the quasimodo2 mutant of Arabidopsis thaliana. [PDF]
Barnes WJ, Zelinsky E, Anderson CT.
europepmc +1 more source
Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells. [PDF]
Harley Y. Tse, Richard Dutton
openalex +1 more source
Protein Phase Separation: A New Phase in Cell Biology.
S. Boeynaems +11 more
semanticscholar +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Advances in Cell Separation: Harnessing DNA Nanomaterials for High-Specificity Recognition and Isolation. [PDF]
Bao H, Yao Y, Tang W, Yang D.
europepmc +1 more source
Two-Dimensional Cell Separation: a High-Throughput Approach to Enhance the Culturability of Bacterial Cells from Environmental Samples. [PDF]
Yadav KK +9 more
europepmc +1 more source

