Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Reply to Fujino et al.: Human Lung Cell Separation Strategies for Translational Research. [PDF]
Duong A, Juvet S, Martinu T.
europepmc +1 more source
Correction to: Cytoplasm protein GFAP magnetic beads construction and application as cell separation target for brain tumors. [PDF]
Zhao Y+11 more
europepmc +1 more source
Separation and isolation of rat natural killer (NK) cells from T cells with monoclonal antibodies. [PDF]
BA Woda+3 more
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Two-Step Acoustic Cell Separation Based on Cell Size and Acoustic Impedance─toward Isolation of Viable Circulating Tumor Cells. [PDF]
Magnusson C+2 more
europepmc +1 more source
A dielectrophoresis-based microfluidic system having double-sided optimized 3D electrodes for label-free cancer cell separation with preserving cell viability. [PDF]
Varmazyari V+4 more
europepmc +1 more source
Cell Separation with Biomaterials
Shigeru Sasakawa, Masaki Miyamoto
openaire +3 more sources
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Numerical study on a facing electrode configuration dielectrophoresis microfluidic system for efficient biological cell separation. [PDF]
Nguyen TH+8 more
europepmc +1 more source