Results 31 to 40 of about 830,435 (266)

Computational Inertial Microfluidics: Optimal Design for Particle Separation

Fluids, 2022
Following the emergence of many blood transfusion-associated diseases, novel passive cell separation technologies, such as microfluidic devices, are increasingly designed and optimized to separate red blood cells (RBCs) and white blood cells (WBCs) from ...
Suvash C. Saha, Isabella Francis, Tanya Nassir   +2 more
doaj   +1 more source

How Donor and Surgical Factors Affect the Viability and Functionality of Human Hepatocytes Isolated From Liver Resections

Frontiers in Medicine, 2022
Liver resections are a significant source of primary human hepatocytes used mainly in artificial liver devices and pharmacological and biomedical studies.
Estela Solanas, Estela Solanas, Nieves Sanchez-Fuentes, Alejandro Serrablo, Alejandro Serrablo, Alberto Lue, Alberto Lue, Sara Lorente, Sara Lorente, Luis Cortés, Luis Cortés, Angel Lanas, Angel Lanas, Angel Lanas, Pedro M. Baptista, Pedro M. Baptista, Pedro M. Baptista, Pedro M. Baptista, M. Trinidad Serrano, M. Trinidad Serrano   +19 more
doaj   +1 more source

Separation of Heterotrophic Microalgae Crypthecodinium cohnii by Dielectrophoresis

Frontiers in Bioengineering and Biotechnology, 2022
Microalgae constitute an abundant source of poly-unsaturated fatty acids which are applied in various biotechnological fields such as pharmaceuticals and food supplement.
Mario Birkholz, Danai Eleni Malti, Stephan Hartmann, Peter Neubauer   +3 more
doaj   +1 more source

Design and Simulation of an Integrated Centrifugal Microfluidic Device for CTCs Separation and Cell Lysis

Micromachines, 2020
Separation of circulating tumor cells (CTCs) from blood samples and subsequent DNA extraction from these cells play a crucial role in cancer research and drug discovery.
Rohollah Nasiri, Amir Shamloo, Javad Akbari, Peyton Tebon, Mehmet R. Dokmeci, Samad Ahadian   +5 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Microfluidic Devices for Blood Fractionation

Micromachines, 2011
Blood, a complex biological fluid, comprises 45% cellular components suspended in protein rich plasma. These different hematologic components perform distinct functions in vivo and thus the ability to efficiently fractionate blood into its individual ...
Chwee Teck Lim, Jongyoon Han, Sha Huang, Han Wei Hou, Ali Asgar S. Bhagat, Wong Cheng Lee   +5 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Microfluidic Separation of Blood Cells Based on the Negative Dielectrophoresis Operated by Three Dimensional Microband Electrodes

Micromachines, 2020
A microfluidic device is presented for the continuous separation of red blood cells (RBCs) and white blood cells (WBCs) in a label-free manner based on negative dielectrophoresis (n-DEP). An alteration of the electric field, generated by pairs of slanted
Tomoyuki Yasukawa, Junko Yamada, Hitoshi Shiku, Tomokazu Matsue, Masato Suzuki   +4 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source