Results 51 to 60 of about 6,529,508 (347)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Rapid, label‐free enrichment of lymphocytes in a closed system using a flow‐through microfluidic device

Bioengineering & Translational Medicine
The majority of adoptive cellular therapies are produced from peripheral mononuclear cells obtained via leukapheresis and further enriched for the cells of interest (e.g., T cells).
Anton Mukhamedshin, Riley C. Reddington, Mai T. P. Dinh, Kumar Abhishek, Mubasher Iqbal, Marc Manheim, Sean C. Gifford, Sergey S. Shevkoplyas   +7 more
doaj   +1 more source

Control of Organ Abscission and Other Cell Separation Processes by Evolutionary Conserved Peptide Signaling

Plants, 2019
Plants both generate and shed organs throughout their lifetime. Cell separation is in function during opening of anthers to release pollen; floral organs are detached after pollination when they have served their purpose; unfertilized flowers are shed ...
Chun-Lin Shi, Renate Marie Alling, Marta Hammerstad, Reidunn B. Aalen   +3 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

A Novel Protocol for Culturing Polarized Proximal Tubular Epithelial Cells from Kidney Biopsies: Enhancing Platforms for Drug Excretion and Nephrotoxicity Studies

Journal of Xenobiotics
The kidneys are integral to homeostasis but are susceptible to nephrotoxic compounds. Proximal tubular epithelial cells (PTECs) mediate drug metabolism and transport and are widely used in preclinical studies.
Tadej Petreski, Lidija Gradišnik, Luka Varda, Polona Kovačič, Jurij Dolenšek, Andraž Stožer, Sebastjan Bevc, Uroš Maver   +7 more
doaj   +1 more source

Rapid Isolation and Concentration of Pathogenic Fungi Using Inertial Focusing on a Chip-Based Platform

Frontiers in Cellular and Infection Microbiology, 2019
Systemic Candida infections remain a leading cause of nosocomial infections in the United States and worldwide. Many challenges remain in achieving rapid, direct diagnosis of fungal bloodstream infections due to limitations of conventional diagnostic ...
Beth Burgwyn Fuchs, Soraya Eatemadpour, Joseph M. Martel-Foley, Shannon Stott, Mehmet Toner, Eleftherios Mylonakis   +5 more
doaj   +1 more source

Characterization and Separation of Live and Dead Yeast Cells Using CMOS-Based DEP Microfluidics

Micromachines, 2021
This study aims at developing a miniaturized CMOS integrated silicon-based microfluidic system, compatible with a standard CMOS process, to enable the characterization, and separation of live and dead yeast cells (as model bio-particle organisms) in a ...
Honeyeh Matbaechi Ettehad, Christian Wenger   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

, 2022
Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K, Yates, LR, Teague, J, Lopez, JI, Gore, M, Rowan, A, Mitchell, TJ, Lynch, AG, Au, L, Stewart, A, Litchfield, K, Turajlic, S, Tarpey, P, Chandra, A, Csabai, I, Swanton, C, Fotiadis, N, Lynch, J, Soultati, A, Challacombe, B, Xu, H, Hazell, S, Stamp, G, Elaidi, R, Horswell, S, Campbell, PJ, Chowdhury, S, Butler, AP, Rudman, S, Wedge, DC, Futreal, PA, Nicol, D, Farmery, JHR, O'Brien, T, Maura, F, McGranahan, N, TRACERx Renal Consortium,, Spain, L, Stewart, GD, Szallasi, Z, Martincorena, I, Stares, M, Fernando, A, Larkin, J, Oudard, S, Pickering, L, Chambers, T, Angelopoulos, N   +47 more
core   +1 more source

OxyHbMeter—a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid—proof of principle

Frontiers in Medical Technology
Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability.
Nikolaos Tachatos, Jan Folkard Willms, Michael Sebastian Gerlt, Kiran Kuruvithadam, Michael Hugelshofer, Kevin Akeret, Jeremy Deuel, Emanuela Keller, Marianne Schmid Daners   +8 more
doaj   +1 more source