Results 241 to 250 of about 14,296,855 (364)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Influence of cell shape on sonoporation efficiency in microbubble-facilitated delivery using micropatterned cell arrays. [PDF]

Sci Rep
Baig MA, Du Y, Zan Z, Fan Z.
europepmc   +1 more source

Interplay of cell shape and division orientation promotes robust morphogenesis of developing epithelia.

Cell, 2014
Fengzhu Xiong, Wenzhe Ma, T. Hiscock, K. Mosaliganti, Andrea Tentner, K. Brakke, Nicolas Rannou, A. Gelas, Lydie Souhait, Ian A. Swinburne, N. Obholzer, Sean Gregory Megason   +11 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape. [PDF]

Cell Rep
Sánchez-Álvarez M, Lolo FN, Sailem H, Fulgoni G, Pascual-Vargas P, Agüera L, Catalá-Montoro M, Arias-García M, López JA, Vázquez J, Del Pozo MÁ, Bakal C.   +11 more
europepmc   +1 more source

PIAS1 Shapes a Tumor-Suppressive Microenvironment by Suppressing Immune Evasion in Oral Squamous Cell Carcinoma [PDF]

Parisa Ghahremanifard, J. An, Ayan Chanda, Angela Chan, Steven C. Nakoneshny, T. Wayne Matthews, Shamir Chandarana, Robert D. Hart, Martin Hyrcza, Joseph C. Dort, Shirin Bonni, Pinaki Bose   +11 more
openalex   +1 more source

Novel Vβ Specific Germline Contacts Shape an Elite Controller T Cell Response

, 2020
Yang Wang, Alexandra Tsitsiklis, Wei Gao, Hunghao Chu, Yan Zhang, Wei Li, Wing Ki Wong, Charlotte M. Deane, David B. Neau, Jill E. Slansky, Paul G. Thomas, Ellen A. Robey, Shaodong Dai   +12 more
openalex   +1 more source

CetZ tubulin-like proteins control archaeal cell shape

Nature, 2014
I. Duggin, Christopher H. S. Aylett, James C. Walsh, K. Michie, Qing Wang, L. Turnbull, E. M. Dawson, E. Harry, C. Whitchurch, L. Amos, J. Löwe   +10 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A dystroglycan-laminin-integrin axis coordinates cell shape remodeling in the developing Drosophila retina. [PDF]

PLoS Biol
Walther RF, Lancaster C, Burden JJ, Pichaud F.   +3 more
europepmc   +1 more source