Results 71 to 80 of about 1,058,178 (293)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Antigen-specific electrophoretic cell separation for immunological investigations [PDF]

, 1989
Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K., Hansen, Ernil, Wustrow, T. P.   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Magnetic Nanoparticles Interact and Pass an In Vitro Co-Culture Blood-Placenta Barrier Model

Nanomaterials, 2018
Magnetic nanoparticles are interesting tools for biomedicine. Before application, critical prerequisites have to be fulfilled. An important issue is the contact and interaction with biological barriers such as the blood-placenta barrier.
Elena K. Müller, Christine Gräfe, Frank Wiekhorst, Christian Bergemann, Andreas Weidner, Silvio Dutz, Joachim H. Clement   +6 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The influence of surface charge on serum protein interaction and cellular uptake: studies with dendritic polyglycerols and dendritic polyglycerol-coated gold nanoparticles

International Journal of Nanomedicine, 2017
Tony Bewersdorff,1 Jonathan Vonnemann,2 Asiye Kanik,1 Rainer Haag,2 Andrea Haase1 1Department of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany; 2Institute of Chemistry and Biochemistry, Freie Universit ...
Bewersdorff T, Vonnemann J, Kanik A, Haag R, Haase A   +4 more
doaj  

Non-specific cellular uptake of surface-functionalized quantum dots

, 2010
We report a systematic empirical study of nanoparticle internalization into cells via non-specific pathways. The nanoparticles were comprised of commercial quantum dots (QDs) that were highly visible under a fluorescence confocal microscope.
Goldys, E M, Kelf, T A, Kim, E J, Sreenivasan, V K A, Sun, J, Zvyagin, A V   +5 more
core   +1 more source

Electrode polarization at the Au, O2(g)/Fe implanted yttria-stabilized zirconia interface [PDF]

, 1992
Ion implantation has been applied to modify the surface properties of yttria-stabilized zirconia (YSZ). A three-electrode cell was used for measuring steady state current-overpotential curves and for determining the electrode impedance.
Boukamp, B.A., Burggraaf, A.J., Hassel, B.A. van   +2 more
core   +2 more sources

Enterococcus faecalis strains show culture heterogeneity in cell surface charge [PDF]

Microbiology, 2006
Adhesion of micro-organisms to biotic and abiotic surfaces is an important virulence factor and involves different types of interactions.Enterococcus faecalis, a human commensal and an important opportunistic pathogen, has the ability to adhere to surfaces. Biliary stents frequently become clogged with bacterial biofilms, withE.
van Merode, Annet, van der Mei, HC, Busscher, HJ, Waar, K, Krom, BP   +4 more
openaire   +3 more sources

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source