Results 131 to 140 of about 8,088,933 (310)

Genitourinary mast cells and survival.

open access: yesTranslational andrology and urology, 2015
Mast cells (MCs) are ubiquitous in the body, but they have historically been associated with allergies, and most recently with regulation of immunity and inflammation. However, it remains a puzzle why so many MCs are located in the diencephalon, which regulates emotions and in the genitourinary tract, including the bladder, prostate, penis, vagina and ...
Theoharides, Theoharis C.   +1 more
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A new mathematical model for radiation cell killing mechanism: Target cumulating model [PDF]

open access: yes, 2009
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin   +3 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The effect of health care expenditures on survival in locally advanced and metastatic Non Small Cell Lung Cancer [PDF]

open access: yes
Context: The significant survival benefit of chemotherapy over best supportive care for locally advanced and metastatic NSCLC has been amply demonstrated in the literature.
Paul Rebattu   +8 more
core  

Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress

open access: yes, 2015
[[abstract]]Summary LKB1 is activated by forming a heterotrimeric complex with STRAD and MO25. Recent studies suggest that LKB1 has pro-oncogenic functions, besides acting as a tumor suppressor.
Lee, SW;Li, CF;Jin, G;Cai, Z;Han, F;Chan, CH;Yang, WL;Li, BK;Rezaeian, Abdol?H;Li, HY;Huang, HY;Lin, HK
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

VIABILIDAD DE LOS MICROORGANISMOS PROBIÓTICOS Lactobacillus casei 01, Lactobacillus acidophilus La-5, Bifidobacterium BB12 DURANTE EL ALMACENAMIENTO DE QUESO COTTAGE VIABILITY OF THE PROBIOTIC MICROORGANISMS Lactobacillus casei 01, Lactobacillus acidophilus La-5, Bifidobacterium BB12 DURING COTTAGE CHEESE SHELF LIFE

open access: yesVitae, 2010
El objetivo del presente trabajo fue evaluar la viabilidad de tres microorganismos considerados probióticos: Lactobacillus casei 01, Bifidobacterium BB12, y Lactobacillus acidophilus La-5, durante la vida útil del queso Cottage (0, 7 y 14, y 7 días ...
Mónica OBANDO C   +4 more
doaj  

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