Results 141 to 150 of about 2,251,671 (317)
Cell Stress: Survival and Apoptosis
, 2016 The multifunctional polydnavirus ANK1 protein: new insights for apoptotis pathway. Mammalians and insects, although phylogenetically distant, share some conserved pathways.
SALVIA, ROSANNA +3 more
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Cryopreservation of cell/hydrogel constructs based on a new cell-assembling technique
, 2009 Organ manufacturing products hold the promise to be used widely in the future for complex organ failings. The cryopreservation of the product is a very important step in the commercialization activities.
Xiaohong Wang +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Editorial: Molecular Mechanisms of Selective Autophagy in Human Disease
Frontiers in Cell and Developmental Biology, 2020 Valentina Cianfanelli +2 more
doaj +1 more source
A new mathematical model for radiation cell killing mechanism: Target cumulating model
, 2009 There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin +3 more
core
Impact of Testicular Germ Cell Tumor Laterality on Survival After Autologous Stem Cell Transplantation and High-Dose Chemotherapy [PDF]
Introduction: This study aimed to evaluate the effect of tumor localization on survival in patients undergoing autologous stem cell transplantation (ASCT), high-dose chemotherapy (HDCT) for recurrent/refractory testicular germ cell tumors (GCT). Methods:
Berkan Karadurmuş +7 more
core +1 more source