Results 311 to 320 of about 13,969,136 (421)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Exploring new mechanisms in cancer molecular pathways and pathogenic cell transformation: PIP4K2A as a prognostic marker and therapeutic target in cutaneous malignant melanoma. [PDF]

Discov Oncol
Luo WF, Song DM, Shen T, He YB, Du HY, Si MJ, Fang LW.   +6 more
europepmc   +1 more source

Cell Surfaces and Neoplastic Transformation [PDF]

, 1970

openalex   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation. [PDF]

PLoS Pathog
Cable JM, Reinoso-Vizcaino NM, White RE, Luftig MA.   +3 more
europepmc   +1 more source

The Effect of 8-Methoxypsoralen-Plus Ultraviolet Light on Cell-Virus Interaction: The Transforming Infection; Effect of PUVA on the Transformation of Baby Hamster Kidney Cells by Polyoma Virus

, 1979
Vera B. Morhenn, James A. Kaye
openalex   +1 more source

Cell Transformation: Tumour Celts Reverted [PDF]

, 1971

openalex   +1 more source

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

Cancer Cell, 2011
Kelly Moran-Crusio, Linsey B. Reavie, A. Shih, O. Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, M. Figueroa, A. Vasanthakumar, Jay P. Patel, Xinyang Zhao, F. Perna, Suveg Pandey, J. Madzo, Chun-Xiao Song, Qing Dai, Chuan He, S. Ibrahim, M. Beran, J. Zavadil, S. Nimer, A. Melnick, L. Godley, I. Aifantis, R. Levine   +23 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Diverse and reprogrammable mechanisms of malignant cell transformation in lymphocytes: pathogenetic insights and translational implications. [PDF]

Front Oncol
Wasik MA, Kim PM, Nejati R.
europepmc   +1 more source