Autologous Hematopoietic Stem Cell Transplantation in Acute Lymphoblastic Lymphoma
Introduction: Despite high remission rates in acute lymphoblastic leukemia (ALL) patients after induction chemotherapies, post- remission therapies needed to avoiding relapse.
Fatemeh Ghaffari +10 more
doaj
Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking. [PDF]
Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular interaction between numerous cell types including macrophages.
Cherqui, Stephanie +4 more
core +1 more source
Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells [PDF]
Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs.
Calonge Cano, Margarita +7 more
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Steroid-Refractory Acute GVHD: Predictors and Outcomes
Patients with steroid-resistant acute graft versus host disease (aGVHD) have a dismal prognosis, with mortality rates in excess of 90%. We sought to identify a subgroup of patients less likely to benefit from initial therapy with corticosteroids as well
Jason R. Westin +12 more
doaj +1 more source
Optimization of Optical and Mechanical Properties of Real Architecture for 3-Dimensional Tissue Equivalents: Towards Treatment of Limbal Epithelial Stem Cell Deficiency [PDF]
Limbal epithelial stem cell (LESC) deficiency can cause blindness. Transplantation of cultured human limbal epithelial cells (hLE) on human amniotic membrane (HAM) can restore vision but clinical graft manufacture can be unreliable.
Daniels, JT +4 more
core
Mesenchymal Stromal Cell Therapy in Solid Organ Transplantation [PDF]
Manuel Alfredo Podestà +2 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Long-term outcome of autologous stem-cell transplantation in relapsed or refractory Hodgkin's lymphoma [PDF]
Bhawna Sirohi +8 more
openalex +1 more source

