Results 141 to 150 of about 521,452 (268)

DP042 | IMPACT OF ANTIFUNGAL PROPHYLAXIS ON TRANSPLANT-RELATED MORTALITY IN MISMATCHED ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT): A PROSPECTIVE EXPERIENCE FROM A SINGLE TRANSPLANT PROGRAM

open access: yesHaematologica
Background In the allogeneic HSCT, the incidence of Invasive Fungal Disease is 7-9% with high rate of mortality. Although the antifungal prophylaxis is crucial, the role of anidulafungin is unknown.
A. Carobene   +19 more
doaj  

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Erratum to: “Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation”

open access: yesHaematologica
Iryna Lastovytska   +14 more
doaj   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Islet Cell Transplantation

open access: yesAnnals of Surgery, 1968
K, Reemtsma   +3 more
openaire   +3 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Unraveling the Role of Zonulin in Allogeneic Hematopoietic Stem Cell Transplantation: A Multicenter Study. [PDF]

open access: yesInt J Mol Sci
Soares Ferreira Junior A   +12 more
europepmc   +1 more source

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