Results 281 to 290 of about 1,036,044 (316)

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

New Insights Into Factors Shaping CMV-Specific T-Cell Polyfunctionality After Hematopoietic Cell Transplantation. [PDF]

Am J Hematol
Sadowska-Klasa A, Lim FY, Xie H, Zamora D, Stevens-Ayers T, Leisenring WM, Edmison BC, De Rosa SC, Mielcarek M, Boeckh M.   +9 more
europepmc   +1 more source

The use of tacrolimus (FK506) and antimetabolites as immunosuppressants for xenotransplantation across closely related rodent species [PDF]

, 1997
Demetris, AJ, Fung, JJ, Murase, N, Rao, AS, Starzl, TE, Valdivia, LA   +5 more
core  

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Impact of Publicly Reported Outcomes on Patient Selection for Hematopoietic Cell Transplantation. [PDF]

JCO Oncol Pract
Strouse C, Juckett M, Logan BR, Estrada-Merly N, Peterson A, Preussler JM, Truong TH, Troy JD, Khera N, Wood WA, Rangarajan HG, Akard LP, Bhatt NS, Sharma A, Rizzo JD, Saber W.   +15 more
europepmc   +1 more source

Comparative Efficacy of Autologous Hematopoietic and Mesenchymal Stem Cell Transplantation in Patients with Systemic Sclerosis: A Systematic Review. [PDF]

J Clin Med
Bakirova S, Baigenzhin A, Tuganbekova S, Askarov M, Chuvakova E, Doskali M, Doszhan A.   +6 more
europepmc   +1 more source

Advancing Hematopoietic Stem Cell Transplantation (HSCT) in Africa: A Pathway to Curing Hematological Disorders. [PDF]

Health Sci Rep
Ogunniyi TJ, Abdulkareem RR, Emiola AR, Bamidele TR, Wazhi GB, Arinde PO, Yisa SS, Makanjuola O, Batisani K, Ilesanmi A.   +9 more
europepmc   +1 more source

Chimerism after whole organ transplantation: an explanation of renal and other organ acceptance [PDF]

, 1997
Demetris, AJ, Murase, N, Rao, AS, Starzl, TE, Thomson, AW, Trucco, M   +5 more
core  

Morphofunctional parameters as predictors of autologous hematopoietic stem cell transplantation outcomes. [PDF]

Front Nutr
Cornago J, Dassen C, Calderón C, Mahíllo I, Pardo L, López-Lorenzo JL, Hormigo AI, Caballero JC, Domingo-González A, Capellán R, Iturrate I, de Camino BP, Sánchez-Fernández MS, Teixeira Á, Del Pecho M, Llamas P, Solán L.   +16 more
europepmc   +1 more source

History of liver and other splanchnic organ transplantation [PDF]

, 1996
Starzl, TE
core