Results 61 to 70 of about 629,742 (317)

Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel

Molecular Therapy: Methods & Clinical Development, 2020
Treatment with axicabtagene ciloleucel (Axi-cel) CD19-CAR-T (chimeric antigen receptor T) cells has been approved for refractory/relapsed diffuse large B cell lymphoma (DLBCL) and primary mediastinal large B cell lymphoma (PMBCL).
Boris Fehse, Anita Badbaran, Carolina Berger, Tanja Sonntag, Kristoffer Riecken, Maria Geffken, Nicolaus Kröger, Francis A. Ayuk   +7 more
doaj   +1 more source

The Immunobiology of Cell Transplantation

Cell Transplantation, 1993
The potential for cell transplantation is enormous, not only in replacement therapy in conditions such as diabetes but also in approaches to gene therapy and the induction of tolerance to organ transplants. Immunobiological aspects of cell transplantation include: 1) isolation and purification of cells for transplantation, 2) preservation of cells, 3 ...
openaire   +3 more sources

Purification of Immature Neuronal Cells from Neural Stem Cell Progeny [PDF]

Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications.
Brent A Reynolds, اسفندياري, ابراهيم, Reynolds, Brent A, Maryam Rahman, Osborne, Geoffrey W, Dennis A Steindler, Adams, David J, Dennis A. Steindler, Takahiro Yasuda, Bjorn Scheffler, Brent A. Reynolds, Scheffler, Bjorn, Mohammad G Golmohammadi, گل محمدی, محمد قاسم, Geoffrey W Osborne, Hassan Azari, David J. Adams, Mohammad G. Golmohammadi, Deleyrolle, Loic P, Steindler, Dennis A, Ebrahim Esfandiari, Loic P Deleyrolle, آذری, حسن, Yasuda1, Takahiro, رحمان, مریم, David J Adams, Loic P. Deleyrolle, Geoffrey W. Osborne   +27 more
core   +1 more source

Melphalan dose in myeloma patients ≥65 years of age undergoing high-dose therapy and autologous stem cell transplantation: a multicentric observational registry study [PDF]

, 2019
The optimal melphalan dose prior to autologous stem cell transplantation (ASCT) is not known for elderly multiple myeloma (MM) patients. We analyzed data of all MM patients ≥65 years (n = 388) enrolled in the observational Swiss Blood Stem Cell ...
Gerber, B., Bargetzi, M., Passweg, J.R., Hitz, F., Barbara Jeker, Pabst Müller, Thomas Niklaus, Thomas Pabst, Jeker, Barbara, Rouven Müller, Lerch, Erika, Wannesson, Luciano, Martina Kleber, Kleber, M., Guido Ghilardi, Anne Cairoli, Ghilardi, G., Hitz, Felicitas, Passweg, Jakob R, Müller, Rouven, Schanz, U., Schmidt, Adrian, Jakob R. Passweg, Kleber, Martina, Adrian Schmidt, Pabst, Thomas, Cairoli, A., Kleber, Martina; https://orcid.org/, Erika Lerch, Jeker, B., Cairoli, Anne, Heim, D., Panagiotis Samaras, Antonia M. S. Müller, Luciano Wannesson, Baldomero, H., Ghilardi, Guido, Bargetzi, Mario, Stussi, Georg, Georg Stussi, Dominik Heim, Müller, R., Schanz, Urs, Rossi, Davide, Michele Ghielmini, Müller, Antonia M S, Samaras, P., Ghielmini, Michele, Helen Baldomero, Felicitas Hitz, Wannesson, L., Davide Rossi, Schmidt, A., Pabst, T., Gerber, Bernhard, Bernhard Gerber, Urs Schanz, Lerch, E., Stussi, G., Mario Bargetzi, Baldomero, Helen, Heim, Dominik, Müller, AMS, Ghielmini, M., Rossi, D., Samaras, Panagiotis   +64 more
core   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Autologous stem cell transplantation for malignancy: a systematic review of the literature [PDF]

, 2000
A systematic review of the literature was undertaken to assess what published evidence is currently available to support the increasing use of autologous stem cell transplantation (ASCT), and to evaluate the published data with regard to the comparative ...
Simnett, S.J., Stewart, L. A., Johnson, Peter W.M., Morgan, G., Sweetenham, J.   +4 more
core  

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]

, 2010
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
H. Kreyenberg, Gerrit Weber, S. Kloss, Bader, Peter, Koscielniak, Ewa, A. Willasch, Selim Kuci, T. Klingebiel, E. Koscielniak, Laer, Dorothee von, Miriam Stais, Willasch, Andre Manfred, D. von Laer, Klingebiel, Thomas, Klöß, Stephan, Stais, Miriam, Kuçi, Selim, Peter Bader, Eva Rettinger, Thomas Klingebiel, B. Voss, Z. Kuci, Kreyenberg, Hermann, Stephan Klöss, G. Weber, Dorothee Von Laer, E. Rettinger, Zyrafete Kuci, Kuçi, Zyrafete, Rettinger, Eva, Bernhard Voss, M. Stais, P. Bader, Hermann Kreyenberg, Weber, Gerrit, Voß, Bernhard, Ewa Koscielniak, Andre Willasch, S. Kuci   +38 more
core   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK

BMC Cancer, 2022
Background The therapeutic armamentarium in multiple myeloma has been significantly broadened by proteasome inhibitors, highly efficient means in controlling of multiple myeloma.
Azam Salimi, Kema Marlen Schroeder, Mirle Schemionek-Reinders, Margherita Vieri, Saskia Maletzke, Deniz Gezer, Behzad Kharabi Masouleh, Iris Appelmann   +7 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source