Results 141 to 150 of about 14,689,883 (354)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. [PDF]

, 2014
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein ...
Valiente, Esmeralda, Donahue, Elizabeth H, Major, Meriel R, Perrior, Trevor R, Firth-Clark, Stuart, Dawson, Lisa F, Littler, Eddy, Wren, Brendan W   +7 more
core   +1 more source

Plant cell wall dynamics and wall-related susceptibility in plant-pathogen interactions

Frontiers in Plant Science, 2014
The cell wall is a dynamic structure that often determines the outcome of the interactions between plants and pathogens. It is a barrier that pathogens need to breach to colonize the plant tissue.
Daniela eBellincampi, Felice eCervone, Vincenzo eLionetti   +2 more
doaj   +1 more source

Stem Cell Transplantation in Friedreich Ataxia: Cure for Leukemia but No Effect on Neurological Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Friedreich Ataxia (FRDA) is a neurodegenerative disorder of children and young adults associated with cardiomyopathy and other systemic complications. We report a 10‐year‐old girl who presented simultaneously with Acute Myelogenous Leukemia and FRDA who was successfully treated for her leukemia with allogeneic hematopoietic stem cell ...
Alexandra Gitman, Niyati Bhandari, Maria Castellaro, Kim Schadt, María Cancio, David R. Lynch   +5 more
wiley   +1 more source

Cell Wall Structure of Coccoid Green Algae as an Important Trade-Off Between Biotic Interference Mechanisms and Multidimensional Cell Growth

Frontiers in Microbiology, 2018
Coccoid green algae can be divided in two groups based on their cell wall structure. One group has a highly chemical resistant cell wall (HR-cell wall) containing algaenan.
Susanne Dunker, Susanne Dunker, Christian Wilhelm, Christian Wilhelm   +3 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Cell wall disassembly is delayed by rhamnogalacturonate lyase gene silencing: potential role in fruit firmness [PDF]

, 2019
Strawberry fruits greatly reduce their quality due to softening during ripening with economically important losses. Texture changes of fleshy fruits during ripening are mainly due to middle lamellae dissolution, cell-to-cell adhesion losses and wall ...
Schückel, J., Quesada-Felice, Miguel Ángel, Knox, P., Matas, A.J., Mercado, J.A., Knox, John Paul, Mercado-Carmona, José Ángel, Molina-Hidalgo, F.J., Muñoz-Blanco, Juan, Pose, S., Matas-Arroyo, Antonio Javier, Blanco-Portales, Rosario, Quesada, M.A., Muñoz-Blanco, J., Ric-Varas, P., Pose-Albacete, Sara, Blanco-Portales, R.   +16 more
core  

Cell-wall hemicelluloses as mobile carbon stores in plants [PDF]

, 2009
Hemicelluloses are the second most abundant polysaccharide in nature after cellulose. So far, the chemical heterogeneity of cell-wall hemicelluloses and the relatively large sample-volume required in existing methods represent major obstacles for large ...
Schädel, Christina
core   +1 more source

Cell Wall Metabolism in Response to Abiotic Stress

Plants, 2015
This review focuses on the responses of the plant cell wall to several abiotic stresses including drought, flooding, heat, cold, salt, heavy metals, light, and air pollutants.
H. Gall, F. Philippe, Jean-Marc Domon, F. Gillet, J. Pelloux, C. Rayon   +5 more
semanticscholar   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source