Results 41 to 50 of about 686,012 (279)

Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans

open access: yesJournal of Cell Science, 2021
Echinocandins such as caspofungin are frontline antifungal drugs that compromise β-1,3 glucan synthesis in the cell wall. Recent reports have shown that fungal cells can resist killing by caspofungin by upregulation of chitin synthesis, thereby ...
Alessandra da Silva Dantas   +7 more
semanticscholar   +1 more source

Critical Assessment of Cell Wall Integrity Factors Contributing to in vivo Echinocandin Tolerance and Resistance in Candida glabrata

open access: yesFrontiers in Microbiology, 2021
Fungal infections are on the rise, and emergence of drug-resistant Candida strains refractory to treatment is particularly alarming. Resistance to azole class antifungals, which have been extensively used worldwide for several decades, is so high in ...
R. Garcia-Rubio   +5 more
semanticscholar   +1 more source

A Transcriptomic Analysis of Xylan Mutants Does Not Support the Existence of a Secondary Cell Wall Integrity System in Arabidopsis

open access: yesFrontiers in Plant Science, 2018
Yeast have long been known to possess a cell wall integrity (CWI) system, and recently an analogous system has been described for the primary walls of plants (PCWI) that leads to changes in plant growth and cell wall composition.
Nuno Faria-Blanc   +4 more
doaj   +1 more source

Induced defense strategies of plants against Ralstonia solanacearum

open access: yesFrontiers in Microbiology, 2023
Plants respond to Ralstonia solanacearum infestation through two layers of immune system (PTI and ETI). This process involves the production of plant-induced resistance. Strategies for inducing resistance in plants include the formation of tyloses, gels,
Haoqi Shi   +5 more
doaj   +1 more source

Inhibitory effect of carvacrol against Alternaria alternata causing goji fruit rot by disrupting the integrity and composition of cell wall

open access: yesFrontiers in Microbiology, 2023
Goji (Lycium barbarum L.) is a widely planted crop in China that is easily infected by the pathogenic fungus Alternaria alternata, which causes rot after harvest. Previous studies showed that carvacrol (CVR) significantly inhibited the mycelial growth of
Lunaike Zhao   +8 more
doaj   +1 more source

Decreased Polysaccharide Feruloylation Compromises Plant Cell Wall Integrity and Increases Susceptibility to Necrotrophic Fungal Pathogens

open access: yesFrontiers in Plant Science, 2016
The complexity of cell wall composition and structure determines the strength, flexibility, and function of the primary cell wall in plants. However, the contribution of the various components to cell wall integrity and function remains unclear ...
Nathan T Reem   +6 more
doaj   +1 more source

Protein Interactions of the Mechanosensory Proteins Wsc2 and Wsc3 for Stress Resistance in Saccharomyces cerevisiae

open access: yesG3: Genes, Genomes, Genetics, 2020
Antifungal drug discovery and design is very challenging because of the considerable similarities in genetic features and metabolic pathways between fungi and humans. However, cell wall composition represents a notable point of divergence.
Vladimir Vélez-Segarra   +19 more
doaj   +1 more source

Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae

open access: yesmBio, 2021
Synthesis and turnover of the bacterial cell wall must be tightly coordinated to avoid structural integrity failure and cell death. Details of this coordination are poorly understood, particularly if and how cell wall turnover enzymes are required for ...
Shannon G. Murphy   +8 more
doaj   +1 more source

Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway [PDF]

open access: yesGenetics, 2011
Abstract The yeast cell wall is a strong, but elastic, structure that is essential not only for the maintenance of cell shape and integrity, but also for progression through the cell cycle. During growth and morphogenesis, and in response to environmental challenges, the cell wall is remodeled in a highly regulated and polarized manner ...
openaire   +2 more sources

Participation of Candida albicans transcription factor RLM1 in cell wall biogenesis and virulence. [PDF]

open access: yesPLoS ONE, 2014
Candida albicans cell wall is important for growth and interaction with the environment. RLM1 is one of the putative transcription factors involved in the cell wall integrity pathway, which plays an important role in the maintenance of the cell wall ...
Yolanda Delgado-Silva   +11 more
doaj   +1 more source

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