Results 41 to 50 of about 185,522 (246)

Interplay of the RNA Exosome Complex and RNA-Binding Protein Ssd1 in Maintaining Cell Wall Stability in Yeast

Microbiology Spectrum, 2021
Yeast cell wall stability is important for cell division and survival under stress conditions. The expression of cell-wall-related proteins is regulated by several pathways involving RNA-binding proteins and RNases.
Ana Novačić, Nada Šupljika, Nikša Bekavac, Bojan Žunar, Igor Stuparević   +4 more
doaj   +1 more source

Cell Wall Integrity Signaling inSaccharomyces cerevisiae [PDF]

Microbiology and Molecular Biology Reviews, 2005
SUMMARYThe yeast cell wall is a highly dynamic structure that is responsible for protecting the cell from rapid changes in external osmotic potential. The wall is also critical for cell expansion during growth and morphogenesis. This review discusses recent advances in understanding the various signal transduction pathways that allow cells to monitor ...
openaire   +2 more sources

Cell Wall Integrity MAPK Pathway Is Essential for Lipid Homeostasis [PDF]

Journal of Biological Chemistry, 2008
The highly conserved yeast cell wall integrity mitogen-activated protein kinase pathway regulates cellular responses to cell wall and membrane stress. We report that this pathway is activated and essential for viability under growth conditions that alter both the abundance and pattern of synthesis and turnover of membrane phospholipids, particularly ...
Lilia R, Nunez, Stephen A, Jesch, Maria L, Gaspar, Claudia, Almaguer, Manuel, Villa-Garcia, Monica, Ruiz-Noriega, Jana, Patton-Vogt, Susan A, Henry   +7 more
openaire   +2 more sources

Comprehensive phenotypic analysis of multiple gene deletions of α-glucan synthase and Crh-transglycosylase gene families in Aspergillus niger highlighting the versatility of the fungal cell wall

The Cell Surface
Multiple paralogs are found in the fungal genomes for several genes that encode proteins involved in cell wall biosynthesis. The genome of A. niger contains five genes encoding putative α-1,3-glucan synthases (AgsA-E) and seven genes encoding putative ...
Katharina J. Ost, Mark Arentshorst, Bruno M. Moerschbacher, Mareike E. Dirks-Hofmeister, Arthur F.J. Ram   +4 more
doaj   +1 more source

Low Cost Hybrid Solar Cell Integration on Wall Tiles [PDF]

ECS Meeting Abstracts, 2011
Abstract not Available.
Reyes Tolosa, María Dolores, Hernández Fenollosa, María de los Ángeles, Camaratta, Rubens, NIEDERSBERG CORREIA, ÁLVARO, Bolink, Hendrik Jan, Soriano, Alejandra, Brine, Hicham, Orozco-Messana, Javier   +7 more
openaire   +3 more sources

The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing, root growth and response to abiotic and biotic stresses.

PLoS Genetics, 2017
Plants actively perceive and respond to perturbations in their cell walls which arise during growth, biotic and abiotic stresses. However, few components involved in plant cell wall integrity sensing have been described to date.
Dieuwertje Van der Does, Freddy Boutrot, Timo Engelsdorf, Jack Rhodes, Joseph F McKenna, Samantha Vernhettes, Iko Koevoets, Nico Tintor, Manikandan Veerabagu, Eva Miedes, Cécile Segonzac, Milena Roux, Alice S Breda, Christian S Hardtke, Antonio Molina, Martijn Rep, Christa Testerink, Grégory Mouille, Herman Höfte, Thorsten Hamann, Cyril Zipfel   +20 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections

BMC Genomics, 2011
Background Mannoproteins construct the outer cover of the fungal cell wall. The covalently linked cell wall protein Ccw12p is an abundant mannoprotein.
Arroyo Javier, Popolo Laura, García-Cantalejo Jesús, Neupert Christine, Piberger Heidi, Ragni Enrico, Aebi Markus, Strahl Sabine   +7 more
doaj   +1 more source

ANXUR receptor-like kinases coordinate cell wall integrity with growth at the pollen tube tip via NADPH oxidases. [PDF]

PLoS Biology, 2013
It has become increasingly apparent that the extracellular matrix (ECM), which in plants corresponds to the cell wall, can influence intracellular activities in ways that go far beyond their supposedly passive mechanical support. In plants, growing cells
Aurélien Boisson-Dernier, Dmytro S Lituiev, Anna Nestorova, Christina Maria Franck, Sharme Thirugnanarajah, Ueli Grossniklaus   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source