Results 41 to 50 of about 6,798,751 (249)

PST1 and ECM33 encode two yeast cell surface GPI proteins important for cell wall integrity

, 2004
Pst1p was previously identified as a protein secreted by yeast regenerating protoplasts, which suggests a role in cell wall construction. ECM33 encodes a protein homologous to Pst1p, and both of them display typical features of GPI-anchored proteins and a
Martínez, Raquel, Gil, Concha, Molero Martín-Portugués, María Gloria, Vázquez, Paloma, Monteoliva Díaz, Lucía, Nombela Cano, César, Pardo, Mercedes   +6 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Salt stress causes cell wall damage in yeast cells lacking mitochondrial DNA

, 2015
The yeast cell wall plays an important role in maintaining cell morphology, cell integrity and response to environmental stresses. Here, we report that salt stress causes cell wall damage in yeast cells lacking mitochondrial DNA (ρ0). Upon salt treatment,
Zhaojie Zhang, Qun Ren, Xiaoming Bao, Qiuqiang Gao, Liang-Chun Liou   +4 more
core   +1 more source

Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment

BMC Plant Biology, 2019
Background Plant cell walls participate in all plant-environment interactions. Maintaining cell wall integrity (CWI) during these interactions is essential.
Timo Engelsdorf, Lars Kjaer, Nora Gigli-Bisceglia, Lauri Vaahtera, Stefan Bauer, Eva Miedes, Alexandra Wormit, Lucinda James, Issariya Chairam, Antonio Molina, Thorsten Hamann   +10 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Chemically Induced Cell Wall Stapling in Bacteria

, 2021
Transpeptidation reinforces the structure of cell-wall peptidoglycan, an extracellular heteropolymer that protects bacteria from osmotic lysis. The clinical success of transpeptidase-inhibiting beta-lactam antibiotics illustrates the essentiality of ...
Aditham, Arjun K., Rivera, Sylvia L., Espaillat, Akbar,, Muriel-Mundo, Chris, Siegrist, M. Sloan, Shieh, Peyton, Cava, Felipe,, Kim, Justin   +7 more
core   +1 more source

A core of cell wall proteins functions in wall integrity responses in Arabidopsis thaliana

Plant Direct
Cell walls surround all plant cells, and their composition and structure are tightly regulated to maintain cellular and organismal homeostasis. In response to wall damage, the cell wall integrity (CWI) system is engaged to ameliorate effects on plant ...
Oyeyemi Ajayi, Ellen Zelinsky, Charles T. Anderson   +2 more
doaj   +1 more source

The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing, root growth and response to abiotic and biotic stresses.

PLoS Genetics, 2017
Plants actively perceive and respond to perturbations in their cell walls which arise during growth, biotic and abiotic stresses. However, few components involved in plant cell wall integrity sensing have been described to date.
Dieuwertje Van der Does, Freddy Boutrot, Timo Engelsdorf, Jack Rhodes, Joseph F McKenna, Samantha Vernhettes, Iko Koevoets, Nico Tintor, Manikandan Veerabagu, Eva Miedes, Cécile Segonzac, Milena Roux, Alice S Breda, Christian S Hardtke, Antonio Molina, Martijn Rep, Christa Testerink, Grégory Mouille, Herman Höfte, Thorsten Hamann, Cyril Zipfel   +20 more
doaj   +1 more source

ANXUR receptor-like kinases coordinate cell wall integrity with growth at the pollen tube tip via NADPH oxidases. [PDF]

PLoS Biology, 2013
It has become increasingly apparent that the extracellular matrix (ECM), which in plants corresponds to the cell wall, can influence intracellular activities in ways that go far beyond their supposedly passive mechanical support. In plants, growing cells
Aurélien Boisson-Dernier, Dmytro S Lituiev, Anna Nestorova, Christina Maria Franck, Sharme Thirugnanarajah, Ueli Grossniklaus   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source