Results 61 to 70 of about 6,798,751 (249)

The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model. [PDF]

, 2015
Aspergillus fumigatus is an opportunistic human pathogen, which causes the life-threatening disease, invasive pulmonary aspergillosis. In fungi, cell wall homeostasis is controlled by the conserved Cell Wall Integrity (CWI) pathway. In A.
Rocha, M. C., Juliana Issa Hori (636421), De Godoy, K. F., Gustavo Henrique Goldman (162715), Juliana Issa Hori, Marina Campos Rocha (786018), Bom, V. L. P., Brown, N. A., Patrícia Alves de Castro, Anderson Ferreira da Cunha, Iran Malavazi, Krissia Franco de Godoy (786019), Patrícia Alves de Castro (532465), Vinícius Leite Pedro Bom, Marina Campos Rocha, Krissia Franco de Godoy, Vinícius Leite Pedro Bom (489549), Goldman, G. H., De Castro, P. A., Malavazi, I., Da Cunha, A. F., Iran Malavazi (81124), Gustavo Henrique Goldman, Anderson Ferreira da Cunha (786020), Hori, J. I., Neil Andrew Brown (162680), Neil Andrew Brown, de Godoy Krissia Franco, Brown Neil Andrew, de Castro Patrícia Alves, Malavazi Iran, Bom Vinícius Leite Pedro, da Cunha Anderson Ferreira, Goldman Gustavo Henrique, Hori Juliana Issa, Brown, Neil, Rocha Marina Campos   +36 more
core   +2 more sources

The basic leucine zipper transcription factor MeaB is critical for biofilm formation, cell wall integrity, and virulence in Aspergillus fumigatus

mSphere
The regulation of fungal cell wall biosynthesis is crucial for cell wall integrity maintenance and directly impacts fungal pathogen virulence. Although numerous genes are involved in fungal cell wall polysaccharide biosynthesis through multiple pathways,
Yuan Chen, Fei Gao, Xiaojin Chen, Siyuan Tao, Peiying Chen, Wei Lin   +5 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria. [PDF]

, 2016
The composition of the Gram-positive cell wall is typically described as containing peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids, which comprise approximately half of the cell wall mass.
Sutcliffe, Iain, van Sorge, Nina, Mistou, Michel-Yves   +2 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Atkinesin-13A modulates cell-wall synthesis and cell expansion in Arabidopsis thaliana via the THESEUS1 pathway. [PDF]

PLoS Genetics, 2014
Growth of plant organs relies on cell proliferation and expansion. While an increasingly detailed picture about the control of cell proliferation is emerging, our knowledge about the control of cell expansion remains more limited.
Ushio Fujikura, Lore Elsaesser, Holger Breuninger, Clara Sánchez-Rodríguez, Alexander Ivakov, Thomas Laux, Kim Findlay, Staffan Persson, Michael Lenhard   +8 more
doaj   +1 more source

Plant Cell Wall Plasticity under Stress Situations

, 2022
This reprint is focused on recent novel research related to the role of plant cell walls under biotic and abiotic stresses, which was published in the Special Issue “Plant Cell Wall Plasticity under Stress Situations” of the Plants journal.

core   +1 more source

Cell Envelope Integrity and Capsule Characterization of Rhodotorula mucilaginosa Strains from Clinical and Environmental Sources

mSphere, 2019
Rhodotorula yeasts are pink, encapsulated basidiomycetes isolated from a variety of environments and clinical settings. They are increasingly linked with disease, particularly central venous catheter infections and meningitis, in immunocompromised ...
Johnathan Yockey, Luke Andres, Moleigh Carson, Jeramia J. Ory, Amy J. Reese   +4 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source