Results 81 to 90 of about 686,012 (279)

Aspergillus fumigatus Hsp90 interacts with the main components of the cell wall integrity pathway and cooperates in heat shock and cell wall stress adaptation

Cellular Microbiology, 2020
The initiation of Aspergillus fumigatus infection occurs via dormant conidia deposition into the airways. Therefore, conidial germination and subsequent hyphal extension and growth occur in a sustained heat shock (HS) environment promoted by the host ...
M. C. Rocha, K. Minari, J. H. T. M. Fabri, Joshua D. Kerkaert, L. Gava, A. F. da Cunha, R. Cramer, J. C. Borges, I. Malavazi   +8 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Atkinesin-13A modulates cell-wall synthesis and cell expansion in Arabidopsis thaliana via the THESEUS1 pathway. [PDF]

PLoS Genetics, 2014
Growth of plant organs relies on cell proliferation and expansion. While an increasingly detailed picture about the control of cell proliferation is emerging, our knowledge about the control of cell expansion remains more limited.
Ushio Fujikura, Lore Elsaesser, Holger Breuninger, Clara Sánchez-Rodríguez, Alexander Ivakov, Thomas Laux, Kim Findlay, Staffan Persson, Michael Lenhard   +8 more
doaj   +1 more source

Cell Wall Integrity Controls Expression of Endoxyloglucan Transferase in Tobacco BY2 Cells [PDF]

Plant and Cell Physiology, 2001
Plant cells can monitor alternations in cell wall architecture. Treatment of tobacco BY2 cells with a cellulase or cellulose biosynthesis inhibitor significantly decreased the mRNA of endoxyloglucan transferase (EXGT). Our results indicated the importance of another gene(s) induced by cell wall defects for the decrease in EXGT mRNA.
N, Nakagawa, N, Sakurai
openaire   +2 more sources

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

PRX9 and PRX40 Are Extensin Peroxidases Essential for Maintaining Tapetum and Microspore Cell Wall Integrity during Arabidopsis Anther Development

The Plant Cell, 2019
PRX9 and PRX40 are essential class III peroxidases that act redundantly to cross-link extensins in tapetal cell walls, which prevents tapetum swelling and enables pollen development. Pollen and microspore development are essential steps in the life cycle
Joseph R. Jacobowitz, W. C. Doyle, J. Weng   +2 more
semanticscholar   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Members of chitin synthase family in Metarhizium acridum differentially affect fungal growth, stress tolerances, cell wall integrity and virulence

PLoS Pathogens, 2019
Chitin is an important component of the fungal cell wall with a family of chitin synthases mediating its synthesis. Here, we report on the genetic characterization of the full suite of seven chitin synthases (MaChsI-VII) identified in the insect ...
Junjie Zhang, Hui Jiang, Yanru Du, N. Keyhani, Yuxian Xia, Kai Jin   +5 more
semanticscholar   +1 more source

The contribution of the nonhomologous region of Prs1 to the maintenance of cell wall integrity and cell viability [PDF]

FEMS Yeast Research, 2013
The gene products of the five-membered PRS gene family in Saccharomyces cerevisiae have been shown to exist as three minimal functional entities, Prs1/Prs3, Prs2/Prs5, and Prs4/Prs5, each capable of supporting cell viability. The Prs1/Prs3 heterodimer can be regarded as the most important because its loss causes temperature sensitivity.
Ugbogu, E.A., Wippler, S., Euston, M., Kouwenhoven, E.N., Kouwenhoven, E.N., de Brouwer, A.P.M., Schweizer, L.M., Schweizer, M.   +7 more
openaire   +3 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source