Results 131 to 140 of about 12,058,080 (291)

Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue

Nature Protocols, 2010
C. Weydert, J. Cullen
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Effect of high cyclic hydrostatic pressure on osteogenesis of mesenchymal stem cells cultured in liquefied micro-compartments. [PDF]

Mater Today Bio, 2023
Ghasemzadeh-Hasankolaei M, Pinto CA, Jesus D, Saraiva JA, Mano JF.   +4 more
europepmc   +1 more source

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells.

Diabetes, 2000
T. Inoguchi, Ping Li, F. Umeda, Hai-Yan Yu, M. Kakimoto, M. Imamura, Tsuyoshi Aoki, T. Etoh, T. Hashimoto, M. Naruse, H. Sano, H. Utsumi, H. Nawata   +12 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Umbilical cord-derived mesenchymal stem cells cultured in the MCL medium for aplastic anemia therapy. [PDF]

Stem Cell Res Ther, 2023
He C, Yang C, Zeng Q, Liu Z, Wang F, Chen Q, Liu T.   +6 more
europepmc   +1 more source

Propagation of prions causing synucleinopathies in cultured cells

Proceedings of the National Academy of Sciences of the United States of America, 2015
A. Woerman, J. Stöhr, A. Aoyagi, R. Rampersaud, Zuzana Krejciova, J. Watts, T. Ohyama, Smita Patel, Kartika Widjaja, Abby Oehler, David W. Sanders, M. Diamond, W. Seeley, L. Middleton, S. Gentleman, Daniel A Mordes, T. Südhof, K. Giles, S. Prusiner   +18 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Dimensional memory in glioblastoma mechanics: Traction force analysis of cells cultured in 2D versus 3D collagen environments. [PDF]

Bioact Mater
Khan M, Kollenz P, Fritzenschaft M, Taheri F, Colombo F, Blumberg JW, Schlotterose L, Schwarz US, Leal-Egaña A, Selhuber-Unkel C.   +9 more
europepmc   +1 more source