Results 21 to 30 of about 333,412 (259)
GPI-AP release in cellular, developmental, and reproductive biology [PDF]
Journal of Lipid Research, 2016 Glycosylphosphatidylinositol-anchored proteins (GPI-APs) contain a covalently linked GPI anchor located on outer cell membranes. GPI-APs are ubiquitously conserved from protozoa to vertebrates and are critical for physiological events such as development, immunity, and neurogenesis in vertebrates.
Fujihara, Yoshitaka, Ikawa, Masahito
openaire +4 more sources
Enhanced germline stem cell longevity in Drosophila diapause
Nature Communications, 2022 Drosophila enter adult reproductive diapause in low temperatures and short day, halting ovarian development yet preserving fertility. Here the authors show that ovarian arrest in diapause is distinct from other stress responses and that despite DNA ...
Sreesankar Easwaran +3 more
doaj +1 more source
Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion
Nature Communications, 2023 Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated
Hema M. Swasthi +4 more
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Disease Models & Mechanisms, 2022 Nucleoporin 98KD (Nup98) is a promiscuous translocation partner in hematological malignancies. Most disease models of Nup98 translocations involve ectopic expression of the fusion protein under study, leaving the endogenous Nup98 loci unperturbed ...
Ajai J. Pulianmackal +6 more
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Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes
Scientific Reports, 2022 Lithium is rare in Earth’s crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments.
Neil White +4 more
doaj +1 more source
Nature Communications, 2019 The daily accumulation of the ZEITLUPE (ZTL) photoreceptor/E3 ubiquitin ligase relies on a light-dependent interaction with GIGANTEA (GI). Here the authors show that GI recruits two deubiquitylases to help stabilize the ZTL-GI complex during the day and ...
Chin-Mei Lee +5 more
doaj +1 more source
Sugar sensation and mechanosensation in the egg-laying preference shift of Drosophila suzukii
eLife, 2022 The agricultural pest Drosophila suzukii differs from most other Drosophila species in that it lays eggs in ripe, rather than overripe, fruit. Previously, we showed that changes in bitter taste sensation accompanied this adaptation (Dweck et al., 2021 ...
Wanyue Wang +5 more
doaj +1 more source
Nature Communications, 2017 Multiple mechanisms regulate Wnt/ß-catenin signalling. Zhanget al. describe a novel regulatory pathway and show that the activator of canonical Wnt signalling, Norrin, triggers endocytosis of its receptor Frizzled4 by promoting Frizzled4 ubiquitination.
Chi Zhang +5 more
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Nature Communications, 2021 Parasitoids exploit host bodies for reproduction, selecting for host defences. A new host defence is reported, in which adult Drosophila accelerate mating behaviour at the sight of certain parasitoid wasps, mediated by the upregulation of a nervous ...
Shimaa A. M. Ebrahim +2 more
doaj +1 more source
XPO5 promotes primary miRNA processing independently of RanGTP
Nature Communications, 2020 XPO5 mediates nuclear export of miRNA hairpin precursors (pre-miRNAs) through a RanGTP-dependent binding. Here the authors employ HITS-CLIP and biochemical analysis and show that XPO5 binds and promotes nuclear processing of clustered pri-miRNAs, with ...
Jingjing Wang +6 more
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