Results 241 to 250 of about 358,177 (298)

Synthetic developmental engineering of human liver organogenesis. [PDF]

Development
Taheri MN, Xiang Y, Ebrahimkhani MR.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

HIDmap: a physiology-based map of human immune system development to support animal-free research and regulatory innovation. [PDF]

Front Immunol
Spruck C, Ladeira L, Kuchovska E, Ostaszewski M, de Caro ER, Corsini E, Geris L, Staumont B, Fayyaz S, Li Q, Grimm F, Fritsche E, Koch K, Tigges J.   +13 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Editorial: Epigenetic regulation in cancer: mechanisms, implications, and therapeutic interventions. [PDF]

Front Cell Dev Biol
Sparaneo A, Chan AKN, Fabrizio FP.
europepmc   +1 more source

Transcriptomic Convergence in Autism Spectrum Disorder: Synaptic, Immune-Glial and RNA-Regulatory Axes in the Human Cerebral Cortex. [PDF]

Int J Dev Neurosci
Kurmashev R.
europepmc   +1 more source

Autism and Neurodegeneration: Distinct Disorders or a Shared Biological Continuum? [PDF]

Brain Sci
Manzo J, Hernández-Aguilar ME.
europepmc   +1 more source

Regionally Distinct Modes of Intestinal-Systemic Vascular Connections in Developing Zebrafish. [PDF]

J Dev Biol
Urasaki A, Kawakami K, Nakagawa O.
europepmc   +1 more source

Maternal Exercise and Offspring Cardiac Regenerative Potential: Roles of Apelin and α-Ketoglutarate. [PDF]

Biology (Basel)
Qin G, Li F, Shi H.
europepmc   +1 more source