Results 11 to 20 of about 358,177 (298)
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway
Nature Communications, 2022 Lysosomal biogenesis errors often result in diseases including mucolipidosis. Here Zhang and Yang et al. identify TMEM251/GCAF as a mannose-6-phosphate modification regulator that is necessary for correct lysosomal targeting, and classify Mucolipidosis ...
Weichao Zhang +14 more
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Whole body regeneration and developmental competition in two botryllid ascidians
EvoDevo, 2021 Background Botryllid ascidians are a group of marine invertebrate chordates that are colonial and grow by repeated rounds of asexual reproduction to form a colony of individual bodies, called zooids, linked by a common vascular network.
Shane Nourizadeh +4 more
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Enhanced germline stem cell longevity in Drosophila diapause
Nature Communications, 2022 Drosophila enter adult reproductive diapause in low temperatures and short day, halting ovarian development yet preserving fertility. Here the authors show that ovarian arrest in diapause is distinct from other stress responses and that despite DNA ...
Sreesankar Easwaran +3 more
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Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion
Nature Communications, 2023 Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated
Hema M. Swasthi +4 more
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Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells [PDF]
, 2021 The conserved adapter protein Scribble (Scrib) plays essential roles in a variety of cellular processes, including polarity establishment, proliferation, and directed cell migration.
Boxem, Mike +8 more
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Coordinated Subcellular Organization in Bacteria
, 2022 HonorsMolecular, Cellular, and Developmental Biology (MCDB)University of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/174732/1/yangsiny ...
Yang, Sinyu
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Disease Models & Mechanisms, 2022 Nucleoporin 98KD (Nup98) is a promiscuous translocation partner in hematological malignancies. Most disease models of Nup98 translocations involve ectopic expression of the fusion protein under study, leaving the endogenous Nup98 loci unperturbed ...
Ajai J. Pulianmackal +6 more
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Complete developmental cycle of Leishmania mexicana in axenic culture [PDF]
, 1994 A complete developmental sequence of Leishmania mexicana has been produced in axenic culture for the first time. This was achieved by manipulation of media, pH and temperature conditions over a period of 16 days.
Bates, P A
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Quantitative analysis of cell shape and the cytoskeleton in developmental biology
, 2020 Computational approaches that enable quantification of microscopy data have revolutionized the field of developmental biology. Due to its inherent complexity, elucidating mechanisms of development requires sophisticated analysis of the structure, shape ...
Martin, Adam C, Yevick, Hannah G.
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Nature Communications, 2019 The daily accumulation of the ZEITLUPE (ZTL) photoreceptor/E3 ubiquitin ligase relies on a light-dependent interaction with GIGANTEA (GI). Here the authors show that GI recruits two deubiquitylases to help stabilize the ZTL-GI complex during the day and ...
Chin-Mei Lee +5 more
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