Results 41 to 50 of about 23,964 (265)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Predictability in cellular automata. [PDF]

open access: yesPLoS ONE, 2014
Modelled as finite homogeneous Markov chains, probabilistic cellular automata with local transition probabilities in (0, 1) always posses a stationary distribution. This result alone is not very helpful when it comes to predicting the final configuration;
Alexandru Agapie   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Cellular automata: Towards possible applications in urban design education and practice | Autômatos celulares: visando possíveis aplicações no ensino e na prática do urbanismo

open access: yesOculum Ensaios, 2019
This article investigates how Cellular Automata have been applied to the design process in the fields of architectural and urban design. It begins by systematically mapping published applications of Cellular Automata in the design process in order to ...
Marcela Noronha Pinto de Oliveira e Sousa   +1 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Cellular Automata Models of Evolution of Transportation Networks [PDF]

open access: yesComputer Science, 2002
We present a new approach to modelling of transportation networks. Supply of resources and their influence on the evolution of the consuming environment is a princqral problem considered.
Mariusz Paszkowski, Pawel Topa
doaj  

Comparison of Evolutionary Development of Cellular Automata Using Various Representations

open access: yesMendel, 2019
A comparative study is presented regarding the evolutionary design of complex multi-state cellular automata. In particular, two-dimensional cellular automata will be considered in combination with pattern development problem as a~case study.
Michal Bidlo
doaj   +1 more source

Number conserving cellular automata: new results on decidability and dynamics [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2003
This paper is a survey on our recent results about number conserving cellular automata. First, we prove the linear time decidability of the property of number conservation. The sequel focuses on dynamical evolutions of number conserving cellular automata.
Bruno Durand   +3 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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