Results 61 to 70 of about 1,964,103 (323)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

On the Dynamical Behavior of Cellular Automata on Finite Groups

IEEE Access
During the last few decades, significant efforts have been devoted to analyze the dynamical behavior of cellular automata (CAs) on cyclic groups, their Cartesian power (referred to as linear cellular automata), and on general abelian groups (referred to ...
Alberto Dennunzio, Enrico Formenti, Luciano Margara   +2 more
doaj   +1 more source

Early Warning Signals for Critical Transitions in Sandpile Cellular Automata

Frontiers in Physics, 2022
The sandpile cellular automata, despite the simplicity of their basic rules, are adequate mathematical models of real-world systems, primarily open nonlinear systems capable to self-organize into the critical state.
Andrey Dmitriev, Andrey Dmitriev, Vasily Kornilov, Victor Dmitriev, Nadezda Abbas   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Bounded Languages Meet Cellular Automata with Sparse Communication [PDF]

, 2009
Cellular automata are one-dimensional arrays of interconnected interacting finite automata. We investigate one of the weakest classes, the real-time one-way cellular automata, and impose an additional restriction on their inter-cell communication by ...
A. Klein, A. Malcher, Andreas Malcher, Bianca Truthe, C. Choffrut, C. Mereghetti, E. Csuhaj-Varjú, G. Pighizzini, Giovanni Pighizzini, H. Umeo, H. Umeo, H. Umeo, J. Mazoyer, Jürgen Dassow, M. Chrobak, M. Kutrib, M. Kutrib, M. Kutrib, M. Kutrib, Martin Kutrib, O. H. Ibarra, O. H. Ibarra, O. H. Ibarra, R. V. Book, R. Vollmar, S. Ginsburg, S. R. Seidel, T. Worsch   +27 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Asynchronous adaptive time step in quantitative cellular automata modeling

BMC Bioinformatics, 2004
Background The behaviors of cells in metazoans are context dependent, thus large-scale multi-cellular modeling is often necessary, for which cellular automata are natural candidates.
Sun Yan, Pang Peter YH, Zhu Hao, Dhar Pawan   +3 more
doaj   +1 more source

Cellular Automata are Generic [PDF]

Electronic Proceedings in Theoretical Computer Science, 2015
Any algorithm (in the sense of Gurevich's abstract-state-machine axiomatization of classical algorithms) operating over any arbitrary unordered domain can be simulated by a dynamic cellular automaton, that is, by a pattern-directed cellular automaton ...
Nachum Dershowitz, Evgenia Falkovich
doaj   +1 more source

Pemodelan Evakuasi Pejalan Kaki di Ruang Koridor dengan Cellular Automata Studi Kasus Gempa Bumi

Techno.Com, 2022
Pemodelan Sistem Evakuasi Pejalan Kaki adalah sebuah sistem pemodelan untuk memodelkan pergerakan objek manusia untuk memberikan analisis pada kejadian evakuasi dalam studi kasus bencana Gempa Bumi.
Muarifin Muarifin, Tri Harsono, Ali Ridho Barakbah   +2 more
doaj   +1 more source

On algebraic cellular automata

, 2011
We investigate some general properties of algebraic cellular automata, i.e., cellular automata over groups whose alphabets are affine algebraic sets and which are locally defined by regular maps.
Ceccherini-Silberstein, Tullio, Coornaert, Michel   +1 more
core   +1 more source