Results 71 to 80 of about 1,932,334 (359)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Predictability in cellular automata. [PDF]
PLoS ONE, 2014 Modelled as finite homogeneous Markov chains, probabilistic cellular automata with local transition probabilities in (0, 1) always posses a stationary distribution. This result alone is not very helpful when it comes to predicting the final configuration;
Alexandru Agapie +3 more
doaj +1 more source
Pseudorandom number generation based on controllable cellular automata
, 2004 A novel Cellular Automata (CA) Controllable CA (CCA) is proposed in this paper. Further, CCA are applied in Pseudorandom Number Generation. Randomness test results on CCA Pseudorandom Number Generators (PRNGs) show that they are better than 1-d CA PRNGs
Zhang, S. +3 more
core +1 more source
Entropy, 2019 In this paper, the properties of the classical confusion–substitution structure and some recently proposed pseudorandom number generators using one-dimensional chaotic maps are investigated.
Wei Zhang, Zhiliang Zhu, Hai Yu
semanticscholar +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Comparison of Evolutionary Development of Cellular Automata Using Various Representations
Mendel, 2019 A comparative study is presented regarding the evolutionary design of complex multi-state cellular automata. In particular, two-dimensional cellular automata will be considered in combination with pattern development problem as a~case study.
Michal Bidlo
doaj +1 more source
RANDOMIZED CELLULAR AUTOMATA [PDF]
International Journal of Modern Physics C, 2007 We define and study a few properties of a class of random automata networks. While regular finite one-dimensional cellular automata are defined on periodic lattices, these automata networks, called randomized cellular automata, are defined on random directed graphs with constant out-degrees and evolve according to cellular automaton rules.
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A Cellular Automata Models of Evolution of Transportation Networks [PDF]
Computer Science, 2002 We present a new approach to modelling of transportation networks. Supply of resources and their influence on the evolution of the consuming environment is a princqral problem considered.
Mariusz Paszkowski, Pawel Topa
doaj