Results 71 to 80 of about 928 (215)

A cellular automaton finite volume method for microstructure evolution during additive manufacturing

open access: yesMaterials & Design, 2019
Additive manufacturing (AM) processes produce unique microstructures compared with other manufacturing processes because of the large thermal gradient, high solidification rate and other local temperature variations caused by the repeated heating and ...
Yanping Lian   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Mathematical model for flood routing based on cellular automaton

open access: yesWater Science and Engineering, 2014
Increasing frequency and severity of flooding have caused tremendous damage in China, requiring more essential countermeasures to alleviate the damage.
Xin Cai, Yi Li, Xing-wen Guo, Wei Wu
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Topographical Analysis of Spatial Patterns Generated by a Cellular Automaton Model of the Proliferation of a Cancer Cell Line In Vitro

open access: yesAnalytical Cellular Pathology, 1997
A well‐suited model to simulate cellular population dynamics is the two‐dimensional cellular automaton model, which consists of a lattice of sites, the value ai,j of each site being updated in discrete time steps according to an identical deterministic ...
Jacqueline Palmari   +3 more
doaj   +1 more source

Blackouts Mechanism Simulation Model of Power System Based on Heterogeneous Cellular Automata

open access: yesZhongguo dianli, 2019
In order to study the mechanism of large blackouts of interconnected power system, a heterogeneous cellular automata model is proposed and used to simulate interconnected power system.
Qun YU, Qi WANG, Na CAO
doaj   +1 more source

Traffic Flow Modeling of Freeway Variable Speed Limit Control Based on the Big Data of Driving Behavior

open access: yesJournal of Advanced Transportation, 2020
Variable speed limit (VSL) control is a flexible restriction on the rate at which motorists can drive on a given stretch of road. Effective VSL control can increase safety and provide clear guidance for motorists.
Xu Qu   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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