Results 81 to 90 of about 27,790 (285)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Level Set Structure of an Integrable Cellular Automaton

Symmetry, Integrability and Geometry: Methods and Applications, 2010
Based on a group theoretical setting a sort of discrete dynamical system is constructed and applied to a combinatorial dynamical system defined on the set of certain Bethe ansatz related objects known as the rigged configurations.
Taichiro Takagi
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

A cellular automaton finite volume method for microstructure evolution during additive manufacturing

Materials & Design, 2019
Additive manufacturing (AM) processes produce unique microstructures compared with other manufacturing processes because of the large thermal gradient, high solidification rate and other local temperature variations caused by the repeated heating and ...
Yanping Lian, Zhengtao Gan, Cheng Yu, Dmitriy Kats, Wing Kam Liu, Gregory J. Wagner   +5 more
doaj   +1 more source

The dynamical origin of the universality classes of spatiotemporal intermittency

, 2008
Studies of the phase diagram of the coupled sine circle map lattice have identified the presence of two distinct universality classes of spatiotemporal intermittency viz.
Ahlers, Alligood, Bagnoli, Bohr, Cencini, Chaté, Chaté, Colovas, Das, Daviaud, Domany, Droz, Ginelli, Grassberger, Grebogi, Grebogi, Hinrichsen, Jabeen, Jabeen, Jabeen, Janaki, Kockelkoren, Kostelich, Kubo, Lai, Lai, Lipowski, Marcq, Marcq, Muñoz, Neelima Gupte, Odor, Pikovsky, Pirat, Pomeau, Pradhan, Rolf, Rupp, Sharma, Stauffer, Takeuchi, Zahera Jabeen, Ódor   +42 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Mathematical model for flood routing based on cellular automaton

Water Science and Engineering, 2014
Increasing frequency and severity of flooding have caused tremendous damage in China, requiring more essential countermeasures to alleviate the damage.
Xin Cai, Yi Li, Xing-wen Guo, Wei Wu
doaj   +1 more source

Cellular automaton supercomputing [PDF]

Many of the models now used in science and engineering are over a century old. And most of them can be implemented on modern digital computers only with considerable difficulty.
Wolfram, Stephen
core   +1 more source

One Dimensional $n$ary Density Classification Using Two Cellular Automaton Rules

, 1998
Suppose each site on a one-dimensional chain with periodic boundary condition may take on any one of the states $0,1,..., n-1$, can you find out the most frequently occurring state using cellular automaton?
Chau, H. F., Siu, L. W., Yan, K. K.
core   +1 more source