Results 111 to 120 of about 1,459,173 (350)
Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis
, 2000 Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''.
Furusawa, Chikara, Kaneko, Kunihiko
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Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
AgronomyCalendula officinalis L. is an important medicinal and ornamental plant possessing multiple bioactive compounds. The in vitro plant regeneration method has recently replaced traditional field cultivation practices of calendula due to its fascinating ...
Tooba Fatima +4 more
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Cellular communication and differentiation [PDF]
Arthritis & Rheumatism, 1979 Harvey Cantor, Edward A. Boyse
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Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells
Stem Cell Reports, 2017 Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we
Yuta Koui +7 more
doaj
Some Causes Underlying Cellular Differentiation [PDF]
, 1958 Author Institution: Department of Botany and Plant Pathology, Ohio State University, Columbus ...
Popham, Richard A.
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Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
eLife, 2017 Aneuploidy and epigenetic alterations have long been associated with carcinogenesis, but it was unknown whether aneuploidy could disrupt the epigenetic states required for cellular differentiation.
Wahid A Mulla +13 more
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Slowdown of growth controls cellular differentiation
Molecular Systems Biology, 2016 AbstractHow can changes in growth rate affect the regulatory networks behavior and the outcomes of cellular differentiation? We address this question by focusing on starvation response in sporulating Bacillus subtilis. We show that the activity of sporulation master regulator Spo0A increases with decreasing cellular growth rate.
Jatin Narula +5 more
openaire +5 more sources