Results 111 to 120 of about 4,342,740 (357)
Multiplex live single-cell transcriptional analysis demarcates cellular functional heterogeneity
eLife, 2019 A fundamental goal in the biological sciences is to determine how individual cells with varied gene expression profiles and diverse functional characteristics contribute to development, physiology, and disease.
Ayhan Atmanli +6 more
doaj +1 more source
BMC Biology, 2014 BackgroundArchaea share a similar microbial lifestyle with bacteria, and not surprisingly then, also exist within matrix-enclosed communities known as biofilms.
Scott Chimileski +2 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Implications of post-pneumonectomy compensatory lung growth in pulmonary physiology and disease
Respiratory Research, 2001 In a number of species, partial pneumonectomy initiates hormonally regulated compensatory growth of the remaining lung lobes that restores normal mass, structure and function. Compensation is qualitatively similar across species, but differs with gender,
Rannels D +2 more
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Multistable switches and their role in cellular differentiation networks
BMC Bioinformatics, 2014 Cellular differentiation during development is controlled by gene regulatory networks (GRNs). This complex process is always subject to gene expression noise.
Ahmadreza Ghaffarizadeh +2 more
semanticscholar +1 more source
Cellular communication and differentiation [PDF]
Arthritis & Rheumatism, 1979 E A, Boyse, H, Cantor
openaire +2 more sources
Cellular differentiation in the leaf
Current Opinion in Cell Biology, 1998 The past year has seen significant advances in our understanding of the mechanisms that regulate cellular differentiation in the leaf. It has been suggested that a common developmental pathway involving MYB-like transcription factors is responsible for distinguishing between cellular identities in the epidermis and that nuclear-cytoplasmic partitioning
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source